Leflunomide


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305 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 dihydroorotate dehydrogenase (quinone) PYRD_HUMAN DHODH Homo sapiens 1723 162 39
2 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 20
3 dihydroorotate dehydrogenase PYRD_MOUSE Dhodh Mus musculus 56749 51 10
4 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 9
5 Bruton tyrosine kinase BTK_HUMAN BTK Homo sapiens 695 383 8
6 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 7
7 cytochrome P450 family 1 subfamily A member 2 CP1A2_HUMAN CYP1A2 Homo sapiens 1544 1532 6
8 aryl hydrocarbon receptor AHR_HUMAN AHR Homo sapiens 196 1409 6
9 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 6
10 matrix metallopeptidase 1 MMP1_HUMAN MMP1 Homo sapiens 4312 1304 6
11 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 6
12 transforming growth factor, beta 1 TGFB1_RAT Tgfb1 Rattus norvegicus 59086 1730 5
13 ribosomal protein S6 kinase B1 KS6B1_HUMAN RPS6KB1 Homo sapiens 6198 764 5
14 interleukin 2 IL2_HUMAN IL2 Homo sapiens 3558 2456 5
15 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 NFKB1_MOUSE Nfkb1 Mus musculus 18033 3161 5
16 signal transducer and activator of transcription 6 STAT6_HUMAN STAT6 Homo sapiens 6778 218 5
17 signal transducer and activator of transcription 6 STAT6_MOUSE Stat6 Mus musculus 20852 216 5
18 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 5
19 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 5
20 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 5
21 RELA proto-oncogene, NF-kB subunit TF65_HUMAN RELA Homo sapiens 5970 1514 4
22 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 4
23 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 4
24 nuclear receptor subfamily 1 group I member 2 NR1I2_HUMAN NR1I2 Homo sapiens 8856 820 4
25 interleukin 4 IL4_HUMAN IL4 Homo sapiens 3565 1529 4
26 cytochrome P450 family 2 subfamily C member 19 CP2CJ_HUMAN CYP2C19 Homo sapiens 1557 1098 4
27 dihydroorotate dehydrogenase (quinone) PYRD_RAT Dhodh Rattus norvegicus 65156 29 4
28 nitric oxide synthase 2 NOS2_HUMAN NOS2 Homo sapiens 4843 2012 4
29 glutamic pyruvic transaminase, soluble ALAT1_MOUSE Gpt Mus musculus 76282 1067 4
30 interleukin 2 IL2_MOUSE Il2 Mus musculus 16183 1527 4
31 interleukin 17A IL17_HUMAN IL17A Homo sapiens 3605 977 3
32 C-C motif chemokine ligand 2 CCL2_RAT Ccl2 Rattus norvegicus 24770 625 3
33 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 3
34 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 3
35 aryl-hydrocarbon receptor AHR_MOUSE Ahr Mus musculus 11622 793 3
36 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 3
37 solute carrier family 17 member 5 S17A5_HUMAN SLC17A5 Homo sapiens 26503 791 3
38 interferon gamma IFNG_MOUSE Ifng Mus musculus 15978 2936 3
39 negative elongation factor complex member C/D NELFD_HUMAN NELFCD Homo sapiens 51497 992 3
40 LCK proto-oncogene, Src family tyrosine kinase LCK_HUMAN LCK Homo sapiens 3932 378 3
41 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 3
42 mitochondrially encoded cytochrome c oxidase II COX2_HUMAN COX2 Homo sapiens 4513 5330 3
43 interferon gamma IFNG_RAT Ifng Rattus norvegicus 25712 928 3
44 C-reactive protein CRP_HUMAN CRP Homo sapiens 1401 2285 3
45 interleukin 13 IL13_HUMAN IL13 Homo sapiens 3596 698 3
46 serum amyloid A1 cluster - SAA@ Homo sapiens 6287 450 2
47 matrix metallopeptidase 3 MMP3_HUMAN MMP3 Homo sapiens 4314 703 2
48 arginase, liver ARGI1_MOUSE Arg1 Mus musculus 11846 289 2
49 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 2
50 IGAN1 - IGAN1 Homo sapiens 60498 249 2