| Protein Name | arginase, liver |
|---|---|
| Organism | Mus musculus |
| Gene ID | 11846 |
| Gene Symbol | Arg1 |
| UniProt | Q61176 (ARGI1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
289
Total Number of Articles : 363 |
Description |
arginase, liver |
| Gene Summary |
Enables arginase activity. Involved in defense response to protozoan; negative regulation of T-helper 2 cell cytokine production; and negative regulation of activated T cell proliferation. Predicted to be located in several cellular components, including extracellular space; mitochondrial outer membrane; and neuronal cell body. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Used to study hyperargininemia. Human ortholog(s) of this gene implicated in asthma; hepatocellular carcinoma; and hyperargininemia. Orthologous to human ARG1 (arginase 1). [provided by Alliance of Genome Resources, Apr 2022] |
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