Protein Name arginase, liver
Organism Mus musculus
Gene ID 11846
Gene Symbol


UniProt Q61176 (ARGI1_MOUSE)
Relationships Total Number of functionally related compound(s) : 289
Total Number of Articles : 363

arginase, liver

Gene Summary

Enables arginase activity. Involved in defense response to protozoan; negative regulation of T-helper 2 cell cytokine production; and negative regulation of activated T cell proliferation. Predicted to be located in several cellular components, including extracellular space; mitochondrial outer membrane; and neuronal cell body. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Used to study hyperargininemia. Human ortholog(s) of this gene implicated in asthma; hepatocellular carcinoma; and hyperargininemia. Orthologous to human ARG1 (arginase 1). [provided by Alliance of Genome Resources, Apr 2022]

  • arginase-1
  • arginase 1, liver
  • arginase I
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