| Protein Name | aryl-hydrocarbon receptor |
|---|---|
| Organism | Mus musculus |
| Gene ID | 11622 |
| Gene Symbol | Ahr |
| UniProt | P30561 (AHR_MOUSE), Q3U5D9 (Q3U5D9_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
793
Total Number of Articles : 1504 |
Description |
aryl-hydrocarbon receptor |
| Gene Summary |
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015] |
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| Properties | |