Protein Name aryl-hydrocarbon receptor
Organism Mus musculus
Gene ID 11622
Gene Symbol

Ahr

UniProt P30561 (AHR_MOUSE), Q3U5D9 (Q3U5D9_MOUSE)
Relationships Total Number of functionally related compound(s) : 793
Total Number of Articles : 1504
Description

aryl-hydrocarbon receptor

Gene Summary

The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]

synonyms
  • aryl hydrocarbon receptor
  • ah receptor
  • dioxin receptor
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Properties