Protein Name dihydroorotate dehydrogenase
Organism Mus musculus
Gene ID 56749
Gene Symbol

Dhodh

UniProt O35435 (PYRD_MOUSE)
Relationships Total Number of functionally related compound(s) : 51
Total Number of Articles : 50
Description

dihydroorotate dehydrogenase

Gene Summary

Enables dihydroorotase activity and dihydroorotate dehydrogenase activity. Involved in 'de novo' UMP biosynthetic process and UDP biosynthetic process. Located in mitochondrion. Is expressed in several structures, including branchial arch; embryo ectoderm; limb bud; respiratory system; and urinary system. Human ortholog(s) of this gene implicated in postaxial acrofacial dysostosis. Orthologous to human DHODH (dihydroorotate dehydrogenase (quinone)). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • dihydroorotate dehydrogenase (quinone), mitochondrial
  • DHOdehase
  • dihydroorotate dehydrogenase, mitochondrial
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Properties