Protein Name aryl hydrocarbon receptor
Organism Homo sapiens
Gene ID 196
Gene Symbol

AHR

UniProt P35869 (AHR_HUMAN), A0A024R9Z8 (A0A024R9Z8_HUMAN)
Relationships Total Number of functionally related compound(s) : 1409
Total Number of Articles : 2695
Description

aryl hydrocarbon receptor

Gene Summary

The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015]

synonyms
  • aryl hydrocarbon receptor
  • AH-receptor
  • ah receptor
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Properties