Protein Name | aryl hydrocarbon receptor |
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Organism | Homo sapiens |
Gene ID | 196 |
Gene Symbol | AHR |
UniProt | P35869 (AHR_HUMAN), A0A024R9Z8 (A0A024R9Z8_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
1409
Total Number of Articles : 2695 |
Description |
aryl hydrocarbon receptor |
Gene Summary |
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015] |
synonyms |
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Properties | |