roxadustat


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68 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 erythropoietin EPO_HUMAN EPO Homo sapiens 2056 1312 21
2 hepcidin antimicrobial peptide HEPC_HUMAN HAMP Homo sapiens 57817 384 9
3 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 9
4 hypoxia inducible factor 1, alpha subunit HIF1A_MOUSE Hif1a Mus musculus 15251 724 8
5 hypoxia inducible factor 1 subunit alpha HIF1A_RAT Hif1a Rattus norvegicus 29560 661 5
6 erythropoietin EPO_MOUSE Epo Mus musculus 13856 515 4
7 endothelial PAS domain protein 1 EPAS1_HUMAN EPAS1 Homo sapiens 2034 257 4
8 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 3
9 erythropoietin EPO_RAT Epo Rattus norvegicus 24335 548 3
10 egl-9 family hypoxia inducible factor 1 EGLN1_HUMAN EGLN1 Homo sapiens 54583 159 3
11 transferrin TRFE_HUMAN TF Homo sapiens 7018 1795 2
12 transforming growth factor, beta 1 TGFB1_MOUSE Tgfb1 Mus musculus 21803 1658 2
13 thyroid hormone receptor beta THB_HUMAN THRB Homo sapiens 7068 117 2
14 endothelial PAS domain protein 1 EPAS1_MOUSE Epas1 Mus musculus 13819 133 2
15 cellular communication network factor 2 CCN2_MOUSE Ccn2 Mus musculus 14219 258 2
16 coagulation factor II, thrombin THRB_HUMAN F2 Homo sapiens 2147 4706 1
17 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 1
18 CD4 molecule CD4_HUMAN CD4 Homo sapiens 920 2744 1
19 interleukin 1 alpha IL1A_RAT Il1a Rattus norvegicus 24493 1116 1
20 superoxide dismutase 1, soluble SODC_MOUSE Sod1 Mus musculus 20655 689 1
21 superoxide dismutase 2, mitochondrial SODM_MOUSE Sod2 Mus musculus 20656 455 1
22 C-reactive protein CRP_HUMAN CRP Homo sapiens 1401 2285 1
23 vasoactive intestinal peptide VIP_HUMAN VIP Homo sapiens 7432 787 1
24 CD14 molecule CD14_HUMAN CD14 Homo sapiens 929 797 1
25 vascular endothelial growth factor A VEGFA_MOUSE Vegfa Mus musculus 22339 1647 1
26 prostaglandin-endoperoxide synthase 2 PGH2_MOUSE Ptgs2 Mus musculus 19225 1538 1
27 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 1
28 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Q3UTR7_MOUSE Agt Mus musculus 11606 860 1
29 galanin and GMAP prepropeptide GALA_RAT Gal Rattus norvegicus 29141 238 1
30 angiotensin converting enzyme 2 ACE2_HUMAN ACE2 Homo sapiens 59272 897 1
31 serine (or cysteine) peptidase inhibitor, clade E, member 1 G5E899_MOUSE Serpine1 Mus musculus 18787 337 1
32 heme oxygenase 1 HMOX1_MOUSE Hmox1 Mus musculus 15368 1339 1
33 protein kinase D1 KPCD1_HUMAN PRKD1 Homo sapiens 5587 227 1
34 vascular endothelial growth factor A VEGFA_RAT Vegfa Rattus norvegicus 83785 1424 1
35 kinase insert domain receptor VGFR2_RAT Kdr Rattus norvegicus 25589 312 1
36 BCL2/adenovirus E1B interacting protein 3 BNIP3_MOUSE Bnip3 Mus musculus 12176 92 1
37 peroxisome proliferator activated receptor gamma PPARG_MOUSE Pparg Mus musculus 19016 1556 1
38 catenin (cadherin associated protein), beta 1 CTNB1_MOUSE Ctnnb1 Mus musculus 12387 1059 1
39 nitric oxide synthase 3, endothelial cell NOS3_MOUSE Nos3 Mus musculus 18127 555 1
40 kinase insert domain receptor VGFR2_HUMAN KDR Homo sapiens 3791 1635 1
41 nuclear factor, erythroid derived 2, like 2 NF2L2_MOUSE Nfe2l2 Mus musculus 18024 2012 1
42 catenin beta 1 CTNB1_RAT Ctnnb1 Rattus norvegicus 84353 669 1
43 carnitine palmitoyltransferase 1a, liver CPT1A_MOUSE Cpt1a Mus musculus 12894 129 1
44 caspase 12 CASPC_MOUSE Casp12 Mus musculus 12364 103 1
45 transforming growth factor, beta receptor I TGFR1_MOUSE Tgfbr1 Mus musculus 21812 98 1
46 ataxin 1 ATX1_MOUSE Atxn1 Mus musculus 20238 114 1
47 FMS-like tyrosine kinase 1 VGFR1_MOUSE Flt1 Mus musculus 14254 180 1
48 sterol regulatory element binding transcription factor 1 SRBP1_MOUSE Srebf1 Mus musculus 20787 409 1
49 peroxisome proliferator activated receptor alpha PPARA_MOUSE Ppara Mus musculus 19013 1052 1
50 BCL2-associated X protein BAX_MOUSE Bax Mus musculus 12028 1197 1