roxadustat


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68 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 erythropoietin EPO_HUMAN EPO Homo sapiens 2056 1312 21
2 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 9
3 hepcidin antimicrobial peptide HEPC_HUMAN HAMP Homo sapiens 57817 384 9
4 hypoxia inducible factor 1, alpha subunit HIF1A_MOUSE Hif1a Mus musculus 15251 724 8
5 hypoxia inducible factor 1 subunit alpha HIF1A_RAT Hif1a Rattus norvegicus 29560 661 5
6 erythropoietin EPO_MOUSE Epo Mus musculus 13856 515 4
7 endothelial PAS domain protein 1 EPAS1_HUMAN EPAS1 Homo sapiens 2034 257 4
8 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 3
9 erythropoietin EPO_RAT Epo Rattus norvegicus 24335 548 3
10 egl-9 family hypoxia inducible factor 1 EGLN1_HUMAN EGLN1 Homo sapiens 54583 159 3
11 transforming growth factor, beta 1 TGFB1_MOUSE Tgfb1 Mus musculus 21803 1658 2
12 endothelial PAS domain protein 1 EPAS1_MOUSE Epas1 Mus musculus 13819 133 2
13 cellular communication network factor 2 CCN2_MOUSE Ccn2 Mus musculus 14219 258 2
14 thyroid hormone receptor beta THB_HUMAN THRB Homo sapiens 7068 117 2
15 transferrin TRFE_HUMAN TF Homo sapiens 7018 1795 2
16 angiotensin converting enzyme 2 ACE2_HUMAN ACE2 Homo sapiens 59272 897 1
17 serine (or cysteine) peptidase inhibitor, clade E, member 1 G5E899_MOUSE Serpine1 Mus musculus 18787 337 1
18 heme oxygenase 1 HMOX1_MOUSE Hmox1 Mus musculus 15368 1339 1
19 protein kinase D1 KPCD1_HUMAN PRKD1 Homo sapiens 5587 227 1
20 vascular endothelial growth factor A VEGFA_RAT Vegfa Rattus norvegicus 83785 1424 1
21 kinase insert domain receptor VGFR2_RAT Kdr Rattus norvegicus 25589 312 1
22 BCL2/adenovirus E1B interacting protein 3 BNIP3_MOUSE Bnip3 Mus musculus 12176 92 1
23 peroxisome proliferator activated receptor gamma PPARG_MOUSE Pparg Mus musculus 19016 1556 1
24 catenin (cadherin associated protein), beta 1 CTNB1_MOUSE Ctnnb1 Mus musculus 12387 1059 1
25 nitric oxide synthase 3, endothelial cell NOS3_MOUSE Nos3 Mus musculus 18127 555 1
26 kinase insert domain receptor VGFR2_HUMAN KDR Homo sapiens 3791 1635 1
27 nuclear factor, erythroid derived 2, like 2 NF2L2_MOUSE Nfe2l2 Mus musculus 18024 2012 1
28 catenin beta 1 CTNB1_RAT Ctnnb1 Rattus norvegicus 84353 669 1
29 carnitine palmitoyltransferase 1a, liver CPT1A_MOUSE Cpt1a Mus musculus 12894 129 1
30 caspase 12 CASPC_MOUSE Casp12 Mus musculus 12364 103 1
31 transforming growth factor, beta receptor I TGFR1_MOUSE Tgfbr1 Mus musculus 21812 98 1
32 ataxin 1 ATX1_MOUSE Atxn1 Mus musculus 20238 114 1
33 FMS-like tyrosine kinase 1 VGFR1_MOUSE Flt1 Mus musculus 14254 180 1
34 sterol regulatory element binding transcription factor 1 SRBP1_MOUSE Srebf1 Mus musculus 20787 409 1
35 peroxisome proliferator activated receptor alpha PPARA_MOUSE Ppara Mus musculus 19013 1052 1
36 BCL2-associated X protein BAX_MOUSE Bax Mus musculus 12028 1197 1
37 microRNA 223 - MIR223 Homo sapiens 407008 140 1
38 actin alpha 2, smooth muscle, aorta ACTA_MOUSE Acta2 Mus musculus 11475 419 1
39 microRNA 223 - Mir223 Rattus norvegicus 100314060 30 1
40 nicotinamide phosphoribosyltransferase NAMPT_HUMAN NAMPT Homo sapiens 10135 402 1
41 cytochrome P450, family 2, subfamily e, polypeptide 1 CP2E1_MOUSE Cyp2e1 Mus musculus 13106 412 1
42 glycogen synthase kinase 3 alpha GSK3A_MOUSE Gsk3a Mus musculus 606496 446 1
43 solute carrier family 16 member 3 MOT4_HUMAN SLC16A3 Homo sapiens 9123 111 1
44 serpin family F member 1 PEDF_HUMAN SERPINF1 Homo sapiens 5176 215 1
45 egl-9 family hypoxia-inducible factor 1 EGLN1_MOUSE Egln1 Mus musculus 112405 70 1
46 aquaporin 2 AQP2_MOUSE Aqp2 Mus musculus 11827 135 1
47 phosducin PHOS_MOUSE Pdc Mus musculus 20028 22 1
48 hepcidin antimicrobial peptide HEPC_RAT Hamp Rattus norvegicus 84604 85 1
49 endothelial PAS domain protein 1 EPAS1_RAT Epas1 Rattus norvegicus 29452 47 1
50 ATPase copper transporting beta - atp7b Danio rerio 556499 4 1