roxadustat


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68 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 erythropoietin EPO_HUMAN EPO Homo sapiens 2056 1312 21
2 hepcidin antimicrobial peptide HEPC_HUMAN HAMP Homo sapiens 57817 384 9
3 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 9
4 hypoxia inducible factor 1, alpha subunit HIF1A_MOUSE Hif1a Mus musculus 15251 724 8
5 hypoxia inducible factor 1 subunit alpha HIF1A_RAT Hif1a Rattus norvegicus 29560 661 5
6 erythropoietin EPO_MOUSE Epo Mus musculus 13856 515 4
7 endothelial PAS domain protein 1 EPAS1_HUMAN EPAS1 Homo sapiens 2034 257 4
8 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 3
9 erythropoietin EPO_RAT Epo Rattus norvegicus 24335 548 3
10 egl-9 family hypoxia inducible factor 1 EGLN1_HUMAN EGLN1 Homo sapiens 54583 159 3
11 cellular communication network factor 2 CCN2_MOUSE Ccn2 Mus musculus 14219 258 2
12 transforming growth factor, beta 1 TGFB1_MOUSE Tgfb1 Mus musculus 21803 1658 2
13 transferrin TRFE_HUMAN TF Homo sapiens 7018 1795 2
14 endothelial PAS domain protein 1 EPAS1_MOUSE Epas1 Mus musculus 13819 133 2
15 thyroid hormone receptor beta THB_HUMAN THRB Homo sapiens 7068 117 2
16 SMAD family member 3 SMAD3_MOUSE Smad3 Mus musculus 17127 343 1
17 CD14 molecule CD14_HUMAN CD14 Homo sapiens 929 797 1
18 solute carrier family 16 member 3 MOT4_HUMAN SLC16A3 Homo sapiens 9123 111 1
19 vascular endothelial growth factor A VEGFA_MOUSE Vegfa Mus musculus 22339 1647 1
20 serpin family F member 1 PEDF_HUMAN SERPINF1 Homo sapiens 5176 215 1
21 prostaglandin-endoperoxide synthase 2 PGH2_MOUSE Ptgs2 Mus musculus 19225 1538 1
22 egl-9 family hypoxia-inducible factor 1 EGLN1_MOUSE Egln1 Mus musculus 112405 70 1
23 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 1
24 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Q3UTR7_MOUSE Agt Mus musculus 11606 860 1
25 aquaporin 2 AQP2_MOUSE Aqp2 Mus musculus 11827 135 1
26 galanin and GMAP prepropeptide GALA_RAT Gal Rattus norvegicus 29141 238 1
27 phosducin PHOS_MOUSE Pdc Mus musculus 20028 22 1
28 hepcidin antimicrobial peptide HEPC_RAT Hamp Rattus norvegicus 84604 85 1
29 angiotensin converting enzyme 2 ACE2_HUMAN ACE2 Homo sapiens 59272 897 1
30 endothelial PAS domain protein 1 EPAS1_RAT Epas1 Rattus norvegicus 29452 47 1
31 serine (or cysteine) peptidase inhibitor, clade E, member 1 G5E899_MOUSE Serpine1 Mus musculus 18787 337 1
32 ATPase copper transporting beta - atp7b Danio rerio 556499 4 1
33 heme oxygenase 1 HMOX1_MOUSE Hmox1 Mus musculus 15368 1339 1
34 protein kinase D1 KPCD1_HUMAN PRKD1 Homo sapiens 5587 227 1
35 vascular endothelial growth factor A VEGFA_RAT Vegfa Rattus norvegicus 83785 1424 1
36 erythropoietin - EPO Macaca fascicularis 101925524 2 1
37 kinase insert domain receptor VGFR2_RAT Kdr Rattus norvegicus 25589 312 1
38 BCL2/adenovirus E1B interacting protein 3 BNIP3_MOUSE Bnip3 Mus musculus 12176 92 1
39 solute carrier family 11 member 2 NRAM2_RAT Slc11a2 Rattus norvegicus 25715 17 1
40 peroxisome proliferator activated receptor gamma PPARG_MOUSE Pparg Mus musculus 19016 1556 1
41 cytochrome b reductase 1 CYBR1_RAT Cybrd1 Rattus norvegicus 295669 10 1
42 catenin (cadherin associated protein), beta 1 CTNB1_MOUSE Ctnnb1 Mus musculus 12387 1059 1
43 nitric oxide synthase 3, endothelial cell NOS3_MOUSE Nos3 Mus musculus 18127 555 1
44 kinase insert domain receptor VGFR2_HUMAN KDR Homo sapiens 3791 1635 1
45 nuclear factor, erythroid derived 2, like 2 NF2L2_MOUSE Nfe2l2 Mus musculus 18024 2012 1
46 catenin beta 1 CTNB1_RAT Ctnnb1 Rattus norvegicus 84353 669 1
47 carnitine palmitoyltransferase 1a, liver CPT1A_MOUSE Cpt1a Mus musculus 12894 129 1
48 caspase 12 CASPC_MOUSE Casp12 Mus musculus 12364 103 1
49 transforming growth factor, beta receptor I TGFR1_MOUSE Tgfbr1 Mus musculus 21812 98 1
50 ataxin 1 ATX1_MOUSE Atxn1 Mus musculus 20238 114 1