Protein Name carnitine palmitoyltransferase 1a, liver
Organism Mus musculus
Gene ID 12894
Gene Symbol

Cpt1a

UniProt P97742 (CPT1A_MOUSE), Q7TQD5 (Q7TQD5_MOUSE), Q3UGT1 (Q3UGT1_MOUSE)
Relationships Total Number of functionally related compound(s) : 129
Total Number of Articles : 154
Description

carnitine palmitoyltransferase 1a, liver

Gene Summary

Enables carnitine O-palmitoyltransferase activity and palmitoleoyltransferase activity. Predicted to be involved in several processes, including carnitine metabolic process; positive regulation of fatty acid beta-oxidation; and regulation of insulin secretion. Predicted to act upstream of or within lipid metabolic process. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; central nervous system; integumental system; sensory organ; and urinary system. Used to study carnitine palmitoyltransferase I deficiency. Human ortholog(s) of this gene implicated in carnitine palmitoyltransferase I deficiency and lipid metabolism disorder. Orthologous to human CPT1A (carnitine palmitoyltransferase 1A). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • carnitine O-palmitoyltransferase 1, liver isoform
  • CPT I
  • CPT1-L
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Properties