| Protein Name | peroxisome proliferator activated receptor alpha |
|---|---|
| Organism | Mus musculus |
| Gene ID | 19013 |
| Gene Symbol | Ppara |
| UniProt | P23204 (PPARA_MOUSE), Q542P9 (Q542P9_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
1052
Total Number of Articles : 2133 |
Description |
peroxisome proliferator activated receptor alpha |
| Gene Summary |
Enables several functions, including DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and lipid binding activity. Involved in several processes, including negative regulation of appetite; positive regulation of fatty acid oxidation; and regulation of gene expression. Acts upstream of or within several processes, including enamel mineralization; positive regulation of cellular biosynthetic process; and wound healing. Predicted to be located in nucleoplasm. Is expressed in several structures, including adipose tissue; early conceptus; heart; liver; and oocyte. Used to study diabetes mellitus. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; hepatocellular carcinoma; lipid metabolism disorder; and myocardial infarction. Orthologous to human PPARA (peroxisome proliferator activated receptor alpha). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |