Protein Name peroxisome proliferator activated receptor alpha
Organism Mus musculus
Gene ID 19013
Gene Symbol


UniProt P23204 (PPARA_MOUSE), Q542P9 (Q542P9_MOUSE)
Relationships Total Number of functionally related compound(s) : 1052
Total Number of Articles : 2133

peroxisome proliferator activated receptor alpha

Gene Summary

Enables several functions, including DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and lipid binding activity. Involved in several processes, including negative regulation of appetite; positive regulation of fatty acid oxidation; and regulation of gene expression. Acts upstream of or within several processes, including enamel mineralization; positive regulation of cellular biosynthetic process; and wound healing. Predicted to be located in nucleoplasm. Is expressed in several structures, including adipose tissue; early conceptus; heart; liver; and oocyte. Used to study diabetes mellitus. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; hepatocellular carcinoma; lipid metabolism disorder; and myocardial infarction. Orthologous to human PPARA (peroxisome proliferator activated receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]

  • peroxisome proliferator-activated receptor alpha
  • nuclear receptor subfamily 1 group C member 1
  • 4933429D07Rik
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