Protein Name nicotinamide phosphoribosyltransferase
Organism Homo sapiens
Gene ID 10135
Gene Symbol

NAMPT

UniProt P43490 (NAMPT_HUMAN), A0A024R718 (A0A024R718_HUMAN)
Relationships Total Number of functionally related compound(s) : 402
Total Number of Articles : 828
Description

nicotinamide phosphoribosyltransferase

Gene Summary

This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10. [provided by RefSeq, Feb 2011]

synonyms
  • nicotinamide phosphoribosyltransferase
  • NAmPRTase
  • pre-B cell-enhancing factor
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Properties