| Protein Name | catenin beta 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 84353 |
| Gene Symbol | Ctnnb1 |
| UniProt | Q9WU82 (CTNB1_RAT), A0A0G2JT93 (A0A0G2JT93_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
669
Total Number of Articles : 919 |
Description |
catenin beta 1 |
| Gene Summary |
Enables cadherin binding activity; ionotropic glutamate receptor binding activity; and nitric-oxide synthase binding activity. Involved in several processes, including cellular response to insulin-like growth factor stimulus; cellular response to lithium ion; and cellular response to mechanical stimulus. Located in several cellular components, including dendritic shaft; intercalated disc; and nuclear membrane. Part of protein-containing complex. Colocalizes with neuron projection. Used to study colon adenocarcinoma and lung carcinoma. Biomarker of Alzheimer's disease and colorectal cancer. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant non-syndromic intellectual disability 19; exudative vitreoretinopathy 7; hepatocellular carcinoma (multiple); reproductive organ cancer (multiple); and urinary system cancer (multiple). Orthologous to human CTNNB1 (catenin beta 1). [provided by Alliance of Genome Resources, Apr 2022] |
| synonyms |
|
| Properties | |