Protein Name glycogen synthase kinase 3 alpha
Organism Mus musculus
Gene ID 606496
Gene Symbol

Gsk3a

UniProt Q2NL51 (GSK3A_MOUSE)
Relationships Total Number of functionally related compound(s) : 446
Total Number of Articles : 540
Description

glycogen synthase kinase 3 alpha

Gene Summary

Enables protein serine/threonine kinase activity and signaling receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of G protein-coupled receptor signaling pathway; and regulation of gene expression. Acts upstream of or within several processes, including cellular response to lithium ion; positive regulation of protein phosphorylation; and protein phosphorylation. Predicted to be located in microtubule. Predicted to be active in axon; cytosol; and nucleus. Is expressed in several structures, including central nervous system; cranium; early conceptus; tongue; and upper jaw. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human GSK3A (glycogen synthase kinase 3 alpha). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • glycogen synthase kinase-3 alpha
  • GSK-3 alpha
  • serine/threonine-protein kinase GSK3A
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Properties