Protein Name erythropoietin
Organism Rattus norvegicus
Gene ID 24335
Gene Symbol

Epo

UniProt P29676 (EPO_RAT)
Relationships Total Number of functionally related compound(s) : 548
Total Number of Articles : 847
Description

erythropoietin

Gene Summary

Predicted to enable cytokine activity; erythropoietin receptor binding activity; and protein kinase activator activity. Involved in several processes, including positive regulation of ERK1 and ERK2 cascade; positive regulation of activated T cell proliferation; and response to dexamethasone. Located in cell body and extracellular space. Used to study retinal detachment and visual epilepsy. Biomarker of cholangiocarcinoma; eye disease (multiple); transient cerebral ischemia; and vascular dementia. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); diabetic angiopathy; familial erythrocytosis 5; ischemia (multiple); and neurodegenerative disease (multiple). Orthologous to human EPO (erythropoietin). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • erythropoietin
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Properties