| Protein Name | caspase 12 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 12364 |
| Gene Symbol | Casp12 |
| UniProt | O08736 (CASPC_MOUSE), E9Q575 (E9Q575_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
103
Total Number of Articles : 129 |
Description |
caspase 12 |
| Gene Summary |
Enables cysteine-type endopeptidase activity. Involved in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and self proteolysis. Acts upstream of or within endoplasmic reticulum unfolded protein response and fibroblast apoptotic process. Located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human CASP12 (caspase 12 (gene/pseudogene)). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |