Protein Name aquaporin 2
Organism Mus musculus
Gene ID 11827
Gene Symbol


UniProt P56402 (AQP2_MOUSE), Q3UQD4 (Q3UQD4_MOUSE)
Relationships Total Number of functionally related compound(s) : 135
Total Number of Articles : 199

aquaporin 2

Gene Summary

Enables water channel activity. Acts upstream of or within cellular response to water deprivation; metanephric collecting duct development; and renal water transport. Located in several cellular components, including apical plasma membrane; perinuclear region of cytoplasm; and recycling endosome. Is expressed in inner ear; metanephros; vestibulo-cochlear ganglion; and vestibulocochlear nerve cochlear component. Used to study nephrogenic diabetes insipidus. Human ortholog(s) of this gene implicated in nephrogenic diabetes insipidus. Orthologous to human AQP2 (aquaporin 2). [provided by Alliance of Genome Resources, Apr 2022]

  • aquaporin-2
  • ADH water channel
  • AQP-2
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