| Protein Name | aquaporin 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 11827 |
| Gene Symbol | Aqp2 |
| UniProt | P56402 (AQP2_MOUSE), Q3UQD4 (Q3UQD4_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
135
Total Number of Articles : 199 |
Description |
aquaporin 2 |
| Gene Summary |
Enables water channel activity. Acts upstream of or within cellular response to water deprivation; metanephric collecting duct development; and renal water transport. Located in several cellular components, including apical plasma membrane; perinuclear region of cytoplasm; and recycling endosome. Is expressed in inner ear; metanephros; vestibulo-cochlear ganglion; and vestibulocochlear nerve cochlear component. Used to study nephrogenic diabetes insipidus. Human ortholog(s) of this gene implicated in nephrogenic diabetes insipidus. Orthologous to human AQP2 (aquaporin 2). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |