Protein Name serpin family F member 1
Organism Homo sapiens
Gene ID 5176
Gene Symbol

SERPINF1

UniProt P36955 (PEDF_HUMAN), A0A140VKF3 (A0A140VKF3_HUMAN)
Relationships Total Number of functionally related compound(s) : 215
Total Number of Articles : 255
Description

serpin family F member 1

Gene Summary

This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI. [provided by RefSeq, Aug 2016]

synonyms
  • pigment epithelium-derived factor
  • alpha-2 antiplasmin
  • cell proliferation-inducing gene 35 protein
Click to show/hide the synonyms
Properties