Sildenafil Citrate


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648 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 phosphodiesterase 5A PDE5A_HUMAN PDE5A Homo sapiens 8654 426 530
2 phosphodiesterase 5A, cGMP-specific PDE5A_MOUSE Pde5a Mus musculus 242202 121 108
3 phosphodiesterase 5A PDE5A_RAT Pde5a Rattus norvegicus 171115 53 49
4 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 27
5 protein kinase cGMP-dependent 1 KGP1_HUMAN PRKG1 Homo sapiens 5592 396 15
6 5'-nucleotidase, cytosolic II 5NTC_HUMAN NT5C2 Homo sapiens 22978 912 14
7 endothelin 1 EDN1_HUMAN EDN1 Homo sapiens 1906 1547 12
8 vascular endothelial growth factor A VEGFA_RAT Vegfa Rattus norvegicus 83785 1424 12
9 nitric oxide synthase 2, inducible NOS2_MOUSE Nos2 Mus musculus 18126 2585 12
10 phosphodiesterase 5A PDE5A_CANLF PDE5A Canis lupus familiaris 403825 24 12
11 cAMP responsive element binding protein 1 CREB1_MOUSE Creb1 Mus musculus 12912 832 11
12 nitric oxide synthase 2 NOS2_RAT Nos2 Rattus norvegicus 24599 1861 11
13 caspase 3 CASP3_RAT Casp3 Rattus norvegicus 25402 2178 10
14 nitric oxide synthase 3, endothelial cell NOS3_MOUSE Nos3 Mus musculus 18127 555 10
15 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 10
16 BCL2, apoptosis regulator BCL2_RAT Bcl2 Rattus norvegicus 24224 1676 10
17 PVR cell adhesion molecule PVR_HUMAN PVR Homo sapiens 5817 160 9
18 myeloperoxidase D3ZGE2_RAT Mpo Rattus norvegicus 303413 1141 9
19 AKT serine/threonine kinase 1 AKT1_RAT Akt1 Rattus norvegicus 24185 2385 8
20 phospholipid phosphatase 1 PLPP1_MOUSE Plpp1 Mus musculus 19012 225 8
21 insulin INS_HUMAN INS Homo sapiens 3630 7950 8
22 BCL2 associated X, apoptosis regulator G3V8T9_RAT Bax Rattus norvegicus 24887 1472 8
23 transient receptor potential cation channel, subfamily C, member 6 Q99N78_RAT Trpc6 Rattus norvegicus 89823 124 7
24 apolipoprotein E APOE_MOUSE Apoe Mus musculus 11816 1371 7
25 B cell leukemia/lymphoma 2 BCL2_MOUSE Bcl2 Mus musculus 12043 1497 7
26 nitric oxide synthase 3 NOS3_HUMAN NOS3 Homo sapiens 4846 1142 7
27 nitric oxide synthase 3 NOS3_RAT Nos3 Rattus norvegicus 24600 745 7
28 nitric oxide synthase 1, neuronal NOS1_MOUSE Nos1 Mus musculus 18125 629 7
29 nitric oxide synthase 2 NOS2_HUMAN NOS2 Homo sapiens 4843 2012 7
30 aldehyde dehydrogenase 7 family member A1 AL7A1_HUMAN ALDH7A1 Homo sapiens 501 269 7
31 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 6
32 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Q3UTR7_MOUSE Agt Mus musculus 11606 860 6
33 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 6
34 brain derived neurotrophic factor BDNF_MOUSE Bdnf Mus musculus 12064 1186 6
35 mitogen activated protein kinase 3 MK03_RAT Mapk3 Rattus norvegicus 50689 1665 6
36 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 6
37 transforming growth factor, beta 1 TGFB1_RAT Tgfb1 Rattus norvegicus 59086 1730 6
38 cytochrome P450 family 2 subfamily C member 9 CP2C9_HUMAN CYP2C9 Homo sapiens 1559 1244 6
39 ATP binding cassette subfamily C member 5 MRP5_HUMAN ABCC5 Homo sapiens 10057 154 5
40 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 5
41 CF transmembrane conductance regulator CFTR_HUMAN CFTR Homo sapiens 1080 1218 5
42 nitric oxide synthase 1 NOS1_RAT Nos1 Rattus norvegicus 24598 760 5
43 heat shock protein family A (Hsp70) member 5 BIP_HUMAN HSPA5 Homo sapiens 3309 965 5
44 interleukin 1 beta IL1B_MOUSE Il1b Mus musculus 16176 2626 5
45 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 5
46 ras homolog family member A RHOA_RAT Rhoa Rattus norvegicus 117273 411 5
47 transient receptor potential cation channel, subfamily C, member 1 TRPC1_RAT Trpc1 Rattus norvegicus 89821 87 5
48 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 5
49 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 5
50 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 4