| Protein Name | cAMP responsive element binding protein 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 12912 |
| Gene Symbol | Creb1 |
| UniProt | Q01147 (CREB1_MOUSE), Q62347 (Q62347_MOUSE), Q547S9 (Q547S9_MOUSE), Q543W0 (Q543W0_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
832
Total Number of Articles : 1614 |
Description |
cAMP responsive element binding protein 1 |
| Gene Summary |
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and cAMP response element binding activity. Involved in several processes, including cellular response to retinoic acid; protein stabilization; and regulation of lipid biosynthetic process. Acts upstream of or within several processes, including cellular response to hepatocyte growth factor stimulus; lung development; and nervous system development. Located in chromatin and nucleus. Part of ATF4-CREB1 transcription factor complex. Is expressed in several structures, including brain; genitourinary system; limb; lung; and maxillary process. Human ortholog(s) of this gene implicated in Parkinson's disease; alcohol dependence; and heroin dependence. Orthologous to human CREB1 (cAMP responsive element binding protein 1). [provided by Alliance of Genome Resources, Jun 2025] |
| synonyms |
|
| Properties | |