Protein Name cAMP responsive element binding protein 1
Organism Mus musculus
Gene ID 12912
Gene Symbol

Creb1

UniProt Q01147 (CREB1_MOUSE), Q62347 (Q62347_MOUSE), Q547S9 (Q547S9_MOUSE), Q543W0 (Q543W0_MOUSE)
Relationships Total Number of functionally related compound(s) : 832
Total Number of Articles : 1614
Description

cAMP responsive element binding protein 1

Gene Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and cAMP response element binding activity. Involved in several processes, including cellular response to retinoic acid; positive regulation of biosynthetic process; and protein stabilization. Acts upstream of or within several processes, including animal organ development; cellular response to hepatocyte growth factor stimulus; and cellular response to leukemia inhibitory factor. Located in chromatin and nucleus. Part of ATF4-CREB1 transcription factor complex. Is expressed in several structures, including genitourinary system; limb; maxillary process; peripheral nervous system ganglion; and telencephalon. Orthologous to human CREB1 (cAMP responsive element binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • cyclic AMP-responsive element-binding protein 1
  • 2310001E10Rik
  • 3526402H21Rik
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Properties