Protein Name | nitric oxide synthase 3 |
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Organism | Rattus norvegicus |
Gene ID | 24600 |
Gene Symbol | Nos3 |
UniProt | Q62600 (NOS3_RAT) |
Relationships |
Total Number of functionally related compound(s) :
745
Total Number of Articles : 1228 |
Description |
nitric oxide synthase 3 |
Gene Summary |
Enables several functions, including Hsp90 protein binding activity; beta-catenin binding activity; and calmodulin binding activity. Involved in several processes, including cellular response to magnesium ion; cellular response to mechanical stimulus; and cellular response to organonitrogen compound. Located in several cellular components, including caveola; nucleolus; and sarcolemma. Used to study artery disease (multiple); irritable bowel syndrome; ischemia (multiple); liver disease (multiple); and retinal disease (multiple). Biomarker of several diseases, including artery disease (multiple); kidney failure (multiple); liver disease (multiple); lung disease (multiple); and overnutrition (multiple). Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease (multiple); artery disease (multiple); eye disease (multiple); reproductive organ cancer (multiple); and vasculitis (multiple). Orthologous to human NOS3 (nitric oxide synthase 3). [provided by Alliance of Genome Resources, Apr 2022] |
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