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391 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 19
2 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 17
3 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 17
4 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 13
5 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 NFKB1_MOUSE Nfkb1 Mus musculus 18033 3161 12
6 interleukin 6 IL6_MOUSE Il6 Mus musculus 16193 3985 12
7 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 11
8 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 11
9 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 9
10 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 9
11 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 9
12 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 9
13 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 8
14 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 8
15 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 8
16 mitogen-activated protein kinase 14 MK14_MOUSE Mapk14 Mus musculus 26416 2012 7
17 interleukin 1 beta IL1B_MOUSE Il1b Mus musculus 16176 2626 7
18 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 6
19 peroxisome proliferator activated receptor gamma PPARG_HUMAN PPARG Homo sapiens 5468 2156 6
20 RELA proto-oncogene, NF-kB subunit TF65_HUMAN RELA Homo sapiens 5970 1514 5
21 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 5
22 interleukin 1 beta Q5BKB0_RAT Il1b Rattus norvegicus 24494 2252 5
23 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 5
24 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 5
25 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 5
26 nitric oxide synthase 2, inducible NOS2_MOUSE Nos2 Mus musculus 18126 2585 5
27 cyclin dependent kinase 2 CDK2_HUMAN CDK2 Homo sapiens 1017 1201 4
28 mitogen-activated protein kinase 8 MK08_MOUSE Mapk8 Mus musculus 26419 1537 4
29 toll-like receptor 4 TLR4_MOUSE Tlr4 Mus musculus 21898 2266 4
30 BCL2 associated X, apoptosis regulator G3V8T9_RAT Bax Rattus norvegicus 24887 1472 4
31 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 4
32 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 4
33 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha IKBA_MOUSE Nfkbia Mus musculus 18035 734 4
34 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 4
35 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 4
36 mitogen-activated protein kinase 1 MK01_MOUSE Mapk1 Mus musculus 26413 1992 4
37 peroxisome proliferator activated receptor gamma PPARG_MOUSE Pparg Mus musculus 19016 1556 4
38 mitogen activated protein kinase 3 MK03_RAT Mapk3 Rattus norvegicus 50689 1665 4
39 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 4
40 caspase 8 CASP8_HUMAN CASP8 Homo sapiens 841 1641 4
41 matrix metallopeptidase 2 MMP2_HUMAN MMP2 Homo sapiens 4313 2342 4
42 myeloperoxidase PERM_MOUSE Mpo Mus musculus 17523 1067 4
43 cyclin dependent kinase inhibitor 1A CDN1A_HUMAN CDKN1A Homo sapiens 1026 1631 4
44 FBJ osteosarcoma oncogene FOS_MOUSE Fos Mus musculus 14281 1086 4
45 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 3
46 apoptosis inducing factor mitochondria associated 1 AIFM1_HUMAN AIFM1 Homo sapiens 9131 318 3
47 interleukin 1 alpha IL1A_MOUSE Il1a Mus musculus 16175 1787 3
48 caspase 3 CASP3_RAT Casp3 Rattus norvegicus 25402 2178 3
49 UDP glucuronosyltransferase family 1 member A9 UD19_HUMAN UGT1A9 Homo sapiens 54600 407 3
50 cyclin dependent kinase inhibitor 1B CDN1B_HUMAN CDKN1B Homo sapiens 1027 588 3