Protein Name interleukin 1 alpha
Organism Mus musculus
Gene ID 16175
Gene Symbol

Il1a

UniProt P01582 (IL1A_MOUSE), Q3U0Y6 (Q3U0Y6_MOUSE)
Relationships Total Number of functionally related compound(s) : 1787
Total Number of Articles : 2542
Description

interleukin 1 alpha

Gene Summary

Enables cytokine activity and interleukin-1 receptor binding activity. Involved in positive regulation of angiogenesis and positive regulation of vascular endothelial growth factor production. Acts upstream of or within several processes, including cell surface receptor signaling pathway; connective tissue replacement involved in inflammatory response wound healing; and positive regulation of cytokine production. Located in cytoplasm and extracellular space. Is expressed in several structures, including alimentary system; brain; hemolymphoid system gland; reproductive system; and respiratory system. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Schnitzler syndrome; autoimmune disease (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to human IL1A (interleukin 1 alpha). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • interleukin-1 alpha
  • IL-1 alpha
  • Il-1a
Click to show/hide the synonyms
Properties