| Protein Name | interleukin 1 alpha |
|---|---|
| Organism | Mus musculus |
| Gene ID | 16175 |
| Gene Symbol | Il1a |
| UniProt | P01582 (IL1A_MOUSE), Q3U0Y6 (Q3U0Y6_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
1787
Total Number of Articles : 2542 |
Description |
interleukin 1 alpha |
| Gene Summary |
Enables cytokine activity. Involved in positive regulation of angiogenesis and positive regulation of vascular endothelial growth factor production. Acts upstream of or within several processes, including connective tissue replacement involved in inflammatory response wound healing; ectopic germ cell programmed cell death; and extrinsic apoptotic signaling pathway in absence of ligand. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and hemolymphoid system. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Schnitzler syndrome; autoimmune disease (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to human IL1A (interleukin 1 alpha). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |