Pemetrexed


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323 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 thymidylate synthetase TYSY_HUMAN TYMS Homo sapiens 7298 800 167
2 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 125
3 dihydrofolate reductase DYR_HUMAN DHFR Homo sapiens 1719 645 43
4 ALK receptor tyrosine kinase ALK_HUMAN ALK Homo sapiens 238 603 40
5 solute carrier family 46 member 1 PCFT_HUMAN SLC46A1 Homo sapiens 113235 110 19
6 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 19
7 solute carrier family 19 member 1 S19A1_HUMAN SLC19A1 Homo sapiens 6573 98 16
8 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 14
9 ROS proto-oncogene 1, receptor tyrosine kinase ROS1_HUMAN ROS1 Homo sapiens 6098 101 12
10 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 11
11 ERCC excision repair 1, endonuclease non-catalytic subunit ERCC1_HUMAN ERCC1 Homo sapiens 2067 239 11
12 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 11
13 methylenetetrahydrofolate reductase MTHR_HUMAN MTHFR Homo sapiens 4524 396 9
14 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 9
15 folylpolyglutamate synthase FOLC_HUMAN FPGS Homo sapiens 2356 161 9
16 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase PUR2_HUMAN GART Homo sapiens 2618 74 8
17 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 7
18 NADH:ubiquinone oxidoreductase subunit B3 NDUB3_HUMAN NDUFB3 Homo sapiens 4709 539 7
19 ret proto-oncogene RET_HUMAN RET Homo sapiens 5979 674 7
20 folate receptor alpha FOLR1_HUMAN FOLR1 Homo sapiens 2348 172 7
21 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 6
22 NK2 homeobox 1 NKX21_HUMAN NKX2-1 Homo sapiens 7080 176 6
23 deoxycytidine kinase DCK_HUMAN DCK Homo sapiens 1633 234 6
24 FOS like 1, AP-1 transcription factor subunit FOSL1_HUMAN FOSL1 Homo sapiens 8061 227 6
25 EMAP like 4 EMAL4_HUMAN EML4 Homo sapiens 27436 62 6
26 proprotein convertase subtilisin/kexin type 9 PCSK9_HUMAN PCSK9 Homo sapiens 255738 518 5
27 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase PUR9_HUMAN ATIC Homo sapiens 471 229 5
28 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 5
29 uracil DNA glycosylase UNG_HUMAN UNG Homo sapiens 7374 231 5
30 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 5
31 solute carrier family 22 member 8 S22A8_HUMAN SLC22A8 Homo sapiens 9376 404 4
32 thymidylate synthase TYSY_MOUSE Tyms Mus musculus 22171 202 4
33 Calcium/calmodulin-dependent protein kinase II KCC2A_DROME CaMKII Drosophila melanogaster 43828 280 4
34 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 4
35 fms related receptor tyrosine kinase 1 VGFR1_HUMAN FLT1 Homo sapiens 2321 547 4
36 thymidine kinase 1 KITH_HUMAN TK1 Homo sapiens 7083 181 4
37 programmed cell death 1 PDCD1_MOUSE Pdcd1 Mus musculus 18566 276 4
38 solute carrier family 29 member 1 (Augustine blood group) S29A1_HUMAN SLC29A1 Homo sapiens 2030 348 4
39 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 4
40 endoplasmic reticulum to nucleus signaling 1 ERN1_HUMAN ERN1 Homo sapiens 2081 451 3
41 CEA cell adhesion molecule 3 CEAM3_HUMAN CEACAM3 Homo sapiens 1084 1053 3
42 TNF receptor superfamily member 10b TR10B_HUMAN TNFRSF10B Homo sapiens 8795 608 3
43 DNA damage inducible transcript 3 DDIT3_HUMAN DDIT3 Homo sapiens 1649 1082 3
44 checkpoint kinase 1 CHK1_HUMAN CHEK1 Homo sapiens 1111 648 3
45 programmed cell death 1 PDCD1_HUMAN PDCD1 Homo sapiens 5133 637 3
46 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 3
47 ATP binding cassette subfamily C member 5 MRP5_HUMAN ABCC5 Homo sapiens 10057 154 3
48 heat shock protein 90 alpha family class A member 1 HS90A_HUMAN HSP90AA1 Homo sapiens 3320 1552 3
49 CD274 antigen PD1L1_MOUSE Cd274 Mus musculus 60533 466 3
50 E2F transcription factor 1 E2F1_HUMAN E2F1 Homo sapiens 1869 403 3