| Protein Name | deoxycytidine kinase |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 1633 |
| Gene Symbol | DCK |
| UniProt | P27707 (DCK_HUMAN), F5CTF3 (F5CTF3_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
234
Total Number of Articles : 390 |
Description |
deoxycytidine kinase |
| Gene Summary |
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008] |
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| Properties | |