Protein Name folate receptor alpha
Organism Homo sapiens
Gene ID 2348
Gene Symbol


UniProt P15328 (FOLR1_HUMAN), A0A024R5H1 (A0A024R5H1_HUMAN)
Relationships Total Number of functionally related compound(s) : 172
Total Number of Articles : 269

folate receptor alpha

Gene Summary

The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]

  • folate receptor alpha
  • FR-alpha
  • KB cells FBP
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