Protein Name NADH:ubiquinone oxidoreductase subunit B3
Organism Homo sapiens
Gene ID 4709
Gene Symbol


UniProt O43676 (NDUB3_HUMAN), A0A024R413 (A0A024R413_HUMAN)
Relationships Total Number of functionally related compound(s) : 539
Total Number of Articles : 1172

NADH:ubiquinone oxidoreductase subunit B3

Gene Summary

This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single-pass membrane protein. Mutations in this gene contribute to mitochondrial complex 1 deficiency. Alternative splicing results in multiple transcript variants encoding the same protein. Humans have multiple pseudogenes of this gene. [provided by RefSeq, Mar 2012]

  • NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
  • NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
  • NADH-ubiquinone oxidoreductase B12 subunit
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