Protein Name FOS like 1, AP-1 transcription factor subunit
Organism Homo sapiens
Gene ID 8061
Gene Symbol

FOSL1

UniProt P15407 (FOSL1_HUMAN), E9PPX2 (E9PPX2_HUMAN), A0A0S2Z595 (A0A0S2Z595_HUMAN), E9PKL5 (E9PKL5_HUMAN)
Relationships Total Number of functionally related compound(s) : 227
Total Number of Articles : 271
Description

FOS like 1, AP-1 transcription factor subunit

Gene Summary

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

synonyms
  • fos-related antigen 1
  • FOS like 1, AP-1 trancription factor subunit
  • FOS-like antigen-1
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Properties