apatinib


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246 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 kinase insert domain receptor VGFR2_HUMAN KDR Homo sapiens 3791 1635 236
2 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 37
3 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 33
4 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 26
5 kinase insert domain protein receptor VGFR2_MOUSE Kdr Mus musculus 16542 475 25
6 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 13
7 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 13
8 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 13
9 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 12
10 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 11
11 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 10
12 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 8
13 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 6
14 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 6
15 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 6
16 ALK receptor tyrosine kinase ALK_HUMAN ALK Homo sapiens 238 603 5
17 vascular endothelial growth factor A VEGFA_MOUSE Vegfa Mus musculus 22339 1647 5
18 alpha fetoprotein FETA_HUMAN AFP Homo sapiens 174 935 5
19 KIT proto-oncogene, receptor tyrosine kinase KIT_HUMAN KIT Homo sapiens 3815 679 5
20 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 5
21 zinc fingers and homeoboxes 2 ZHX2_HUMAN ZHX2 Homo sapiens 22882 627 4
22 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 4
23 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 4
24 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 4
25 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 4
26 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 4
27 SRC proto-oncogene, non-receptor tyrosine kinase SRC_HUMAN SRC Homo sapiens 6714 2142 4
28 cytochrome P450 family 2 subfamily D member 6 CP2D6_HUMAN CYP2D6 Homo sapiens 1565 1531 4
29 albumin ALBU_HUMAN ALB Homo sapiens 213 5631 3
30 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 3
31 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 3
32 glycogen synthase kinase 3 alpha GSK3A_HUMAN GSK3A Homo sapiens 2931 623 3
33 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 3
34 interleukin 17A IL17_HUMAN IL17A Homo sapiens 3605 977 3
35 kinase insert domain receptor VGFR2_RAT Kdr Rattus norvegicus 25589 312 3
36 ret proto-oncogene RET_HUMAN RET Homo sapiens 5979 674 3
37 Janus kinase 2 JAK2_HUMAN JAK2 Homo sapiens 3717 1038 3
38 ADAM metallopeptidase domain 17 ADA17_HUMAN ADAM17 Homo sapiens 6868 446 3
39 platelet derived growth factor receptor beta PGFRB_HUMAN PDGFRB Homo sapiens 5159 417 2
40 annexin A5 ANXA5_HUMAN ANXA5 Homo sapiens 308 1785 2
41 MIR7-3 host gene - MIR7-3HG Homo sapiens 284424 679 2
42 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 2
43 interferon gamma IFNG_HUMAN IFNG Homo sapiens 3458 3371 2
44 nucleoporin 62 NUP62_HUMAN NUP62 Homo sapiens 23636 610 2
45 mucin 16, cell surface associated MUC16_HUMAN MUC16 Homo sapiens 94025 408 2
46 CD4 molecule CD4_HUMAN CD4 Homo sapiens 920 2744 2
47 vimentin VIME_HUMAN VIM Homo sapiens 7431 1102 2
48 Moloney sarcoma oncogene MOS_MOUSE Mos Mus musculus 17451 147 2
49 interferon gamma IFNG_MOUSE Ifng Mus musculus 15978 2936 2
50 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 2