apatinib

mechanistic target of rapamycin kinase ; Homo sapiens







13 Article(s)
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1 33978839 Autophagy inhibitor potentiates the antitumor efficacy of apatinib in uterine sarcoma by stimulating PI3K/Akt/mTOR pathway. 2021 Aug 4
2 34077013 Apatinib strengthens the anti-tumor effect of cisplatin in thyroid carcinoma through downregulating VEGFR2. 2021 Mar-Apr 4
3 34229754 Apatinib induces endoplasmic reticulum stress-mediated apoptosis and autophagy and potentiates cell sensitivity to paclitaxel via the IRE-1α-AKT-mTOR pathway in esophageal squamous cell carcinoma. 2021 Jul 6 4
4 34249438 Targeting ERK combined with apatinib may be a promising therapeutic strategy for treating oral squamous cell carcinoma. 2021 2
5 34868934 Anti-Tumor Effect of Apatinib and Relevant Mechanisms in Liposarcoma. 2021 2
6 32126236 Apatinib exhibits cytotoxicity toward leukemia cells by targeting VEGFR2-mediated prosurvival signaling and angiogenesis. 2020 May 1 1
7 32209188 [Apatinib Combined with CCI-779 Inhibits the Proliferation and Migration of Small Cell Lung Cancer NCI-H446 Cells In Vitro]. 2020 Apr 20 2
8 32219060 Apatinib Inhibits Cell Proliferation and Induces Autophagy in Human Papillary Thyroid Carcinoma via the PI3K/Akt/mTOR Signaling Pathway. 2020 3
9 32788939 Apatinib induces apoptosis and autophagy via the PI3K/AKT/mTOR and MAPK/ERK signaling pathways in neuroblastoma. 2020 Oct 2
10 30863481 Apatinib Promotes Apoptosis of Pancreatic Cancer Cells through Downregulation of Hypoxia-Inducible Factor-1α and Increased Levels of Reactive Oxygen Species. 2019 1
11 31079851 Apatinib enhanced anti-tumor activity of cisplatin on triple-negative breast cancer through inhibition of VEGFR-2. 2019 Jul 1
12 30301881 Apatinib-induced protective autophagy and apoptosis through the AKT-mTOR pathway in anaplastic thyroid cancer. 2018 Oct 9 4
13 29085592 Apatinib has anti-tumor effects and induces autophagy in colon cancer cells. 2017 Sep 1