Sirolimus


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2874 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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51 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta PK3CD_HUMAN PIK3CD Homo sapiens 5293 775 29
52 nucleoporin 62 NUP62_HUMAN NUP62 Homo sapiens 23636 610 28
53 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 28
54 microtubule associated protein 1 light chain 3 alpha MLP3A_HUMAN MAP1LC3A Homo sapiens 84557 710 27
55 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 27
56 ubiquitin associated and SH3 domain containing B UBS3B_HUMAN UBASH3B Homo sapiens 84959 147 27
57 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 26
58 ribosomal protein S6 RS6_HUMAN RPS6 Homo sapiens 6194 149 26
59 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 25
60 regulatory associated protein of MTOR complex 1 RPTOR_HUMAN RPTOR Homo sapiens 57521 98 25
61 RPTOR independent companion of MTOR complex 2 RICTR_HUMAN RICTOR Homo sapiens 253260 219 24
62 beclin 1 BECN1_RAT Becn1 Rattus norvegicus 114558 319 24
63 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 24
64 Ras homolog, mTORC1 binding RHEB_HUMAN RHEB Homo sapiens 6009 107 23
65 interleukin 10 IL10_HUMAN IL10 Homo sapiens 3586 2075 23
66 interferon gamma IFNG_MOUSE Ifng Mus musculus 15978 2936 23
67 nitrogen-responsive transcriptional regulator GLN3 GLN3_YEAST GLN3 Saccharomyces cerevisiae S288C 856763 60 23
68 transforming growth factor, beta 1 TGFB1_MOUSE Tgfb1 Mus musculus 21803 1658 22
69 protein kinase AMP-activated catalytic subunit alpha 2 AAPK2_HUMAN PRKAA2 Homo sapiens 5563 919 22
70 interleukin 2 receptor subunit alpha IL2RA_HUMAN IL2RA Homo sapiens 3559 705 22
71 FK506 binding protein 1a FKB1A_MOUSE Fkbp1a Mus musculus 14225 47 22
72 phosphatase and tensin homolog PTEN_MOUSE Pten Mus musculus 19211 532 21
73 microtubule-associated protein 1 light chain 3 alpha MLP3A_MOUSE Map1lc3a Mus musculus 66734 265 21
74 cytochrome P450 family 3 subfamily A member 5 CP3A5_HUMAN CYP3A5 Homo sapiens 1577 539 21
75 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 20
76 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 20
77 interleukin 1 beta IL1B_MOUSE Il1b Mus musculus 16176 2626 19
78 protein kinase AMP-activated non-catalytic subunit beta 1 AAKB1_HUMAN PRKAB1 Homo sapiens 5564 368 19
79 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 19
80 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 19
81 forkhead box P3 FOXP3_MOUSE Foxp3 Mus musculus 20371 525 19
82 protein tyrosine kinase 2 beta FAK2_HUMAN PTK2B Homo sapiens 2185 848 19
83 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 19
84 annexin A6 ANXA6_HUMAN ANXA6 Homo sapiens 309 161 18
85 transformation related protein 53, pseudogene - Trp53-ps Mus musculus 22060 1552 18
86 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 18
87 neurofibromin 1 NF1_HUMAN NF1 Homo sapiens 4763 413 17
88 vascular endothelial growth factor A VEGFA_RAT Vegfa Rattus norvegicus 83785 1424 17
89 phosphatidylinositol kinase-related protein kinase TOR1 TOR1_YEAST TOR1 Saccharomyces cerevisiae S288C 853529 49 17
90 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 16
91 FKBP prolyl isomerase 1A pseudogene 1 - FKBP1AP1 Homo sapiens 2282 39 16
92 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 16
93 CD34 molecule CD34_HUMAN CD34 Homo sapiens 947 1218 16
94 unc-51 like autophagy activating kinase 1 ULK1_HUMAN ULK1 Homo sapiens 8408 234 16
95 caspase 3 CASP3_RAT Casp3 Rattus norvegicus 25402 2178 16
96 interleukin 1 alpha IL1A_HUMAN IL1A Homo sapiens 3552 2741 15
97 mitogen-activated protein kinase 1 MK01_MOUSE Mapk1 Mus musculus 26413 1992 15
98 apolipoprotein E APOE_MOUSE Apoe Mus musculus 11816 1371 15
99 target of rapamycin TOR_ARATH TOR Arabidopsis thaliana 841427 64 15
100 mechanistic target of rapamycin kinase Q06RG6_DANRE mtor Danio rerio 324254 41 15