| Protein Name | Ras homolog, mTORC1 binding |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 6009 |
| Gene Symbol | RHEB |
| UniProt | Q15382 (RHEB_HUMAN), A0A090N900 (A0A090N900_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
107
Total Number of Articles : 168 |
Description |
Ras homolog, mTORC1 binding |
| Gene Summary |
This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008] |
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