| 1 |
34370147 | Synergistic effects of Rapamycin and Fluorouracil to treat a gastric tumor in a PTEN conditional deletion mouse model. | 2022 Jan |
2 |
| 2 |
34275490 | Pharmacological inhibition of the PI3K/PTEN/Akt and mTOR signalling pathways limits follicle activation induced by ovarian cryopreservation and in vitro culture. | 2021 Jul 19 |
1 |
| 3 |
30816216 | Suppression of Akt-mTOR pathway rescued the social behavior in Cntnap2-deficient mice. | 2019 Feb 28 |
1 |
| 4 |
29716894 | Hamartoma-like lesions in the mouse retina: an animal model of Pten hamartoma tumour syndrome. | 2018 May 21 |
1 |
| 5 |
27524416 | mTOR promotes pituitary tumor development through activation of PTTG1. | 2017 Feb 16 |
1 |
| 6 |
27660040 | Dietary rapamycin supplementation reverses age-related vascular dysfunction and oxidative stress, while modulating nutrient-sensing, cell cycle, and senescence pathways. | 2017 Feb |
1 |
| 7 |
27050906 | mTOR transcriptionally and post-transcriptionally regulates Npm1 gene expression to contribute to enhanced proliferation in cells with Pten inactivation. | 2016 May 18 |
1 |
| 8 |
25646773 | Livers with constitutive mTORC1 activity resist steatosis independent of feedback suppression of Akt. | 2015 |
1 |
| 9 |
25752454 | mTOR inhibition suppresses established epilepsy in a mouse model of cortical dysplasia. | 2015 Apr |
1 |
| 10 |
25985273 | Phosphatidylinositol 3-kinase signaling determines kidney size. | 2015 Jun |
1 |
| 11 |
23326514 | Pharmacological inhibition of mTORC1 prevents over-activation of the primordial follicle pool in response to elevated PI3K signaling. | 2013 |
1 |
| 12 |
21212363 | Suppression of leukemia development caused by PTEN loss. | 2011 Jan 25 |
1 |
| 13 |
21695255 | Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN. | 2011 |
1 |
| 14 |
21973019 | Inhibition of the mammalian target of rapamycin blocks epilepsy progression in NS-Pten conditional knockout mice. | 2011 Nov |
1 |
| 15 |
20498714 | Accelerated wound healing by mTOR activation in genetically defined mouse models. | 2010 May 13 |
1 |
| 16 |
20620173 | Posttranslational regulation of membrane type 1-matrix metalloproteinase (MT1-MMP) in mouse PTEN null prostate cancer cells: Enhanced surface expression and differential O-glycosylation of MT1-MMP. | 2010 Nov |
1 |
| 17 |
21504089 | Rapamycin treatment suppresses epileptogenic activity in conditional Pten knockout mice. | 2010 Jul 1 |
1 |
| 18 |
19395652 | PTEN deficiency is fully penetrant for prostate adenocarcinoma in C57BL/6 mice via mTOR-dependent growth. | 2009 May |
1 |
| 19 |
17496901 | The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas. | 2007 Jun |
1 |
| 20 |
16243031 | Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(+/-) mice. | 2005 Oct 25 |
1 |
| 21 |
12414639 | Inhibitors of mTOR reverse doxorubicin resistance conferred by PTEN status in prostate cancer cells. | 2002 Nov 1 |
1 |