Protein Name unc-51 like autophagy activating kinase 1
Organism Homo sapiens
Gene ID 8408
Gene Symbol

ULK1

UniProt O75385 (ULK1_HUMAN)
Relationships Total Number of functionally related compound(s) : 234
Total Number of Articles : 327
Description

unc-51 like autophagy activating kinase 1

Gene Summary

Enables identical protein binding activity; protein serine/threonine kinase activity; and small GTPase binding activity. Involved in several processes, including autophagosome assembly; positive regulation by symbiont of host autophagy; and protein phosphorylation. Located in autophagosome; cytosol; and phagophore assembly site membrane. Is extrinsic component of autophagosome membrane; extrinsic component of omegasome membrane; and extrinsic component of phagophore assembly site membrane. Part of Atg1/ULK1 kinase complex. [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • serine/threonine-protein kinase ULK1
  • ATG1 autophagy related 1 homolog
  • autophagy-related protein 1 homolog
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Properties