Protein Name nitrogen-responsive transcriptional regulator GLN3
Organism Saccharomyces cerevisiae S288C
Gene ID 856763
Gene Symbol

GLN3

UniProt P18494 (GLN3_YEAST)
Relationships Total Number of functionally related compound(s) : 60
Total Number of Articles : 122
Description

nitrogen-responsive transcriptional regulator GLN3

Gene Summary

Enables DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of protein localization by the Cvt pathway and regulation of transcription by RNA polymerase II. Located in cytosol and nucleus. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; X-linked recessive disease (multiple); adenocarcinoma (multiple); congenital heart disease (multiple); and hematologic cancer (multiple). Orthologous to several human genes including GATA1 (GATA binding protein 1); GATA2 (GATA binding protein 2); and GATA3 (GATA binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • nitrogen-responsive transcriptional regulator GLN3
  • YER040W
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Properties