Protein Name | nitrogen-responsive transcriptional regulator GLN3 |
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Organism | Saccharomyces cerevisiae S288C |
Gene ID | 856763 |
Gene Symbol | GLN3 |
UniProt | P18494 (GLN3_YEAST) |
Relationships |
Total Number of functionally related compound(s) :
60
Total Number of Articles : 122 |
Description |
nitrogen-responsive transcriptional regulator GLN3 |
Gene Summary |
Enables DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of protein localization by the Cvt pathway and regulation of transcription by RNA polymerase II. Located in cytosol and nucleus. Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; X-linked recessive disease (multiple); adenocarcinoma (multiple); congenital heart disease (multiple); and hematologic cancer (multiple). Orthologous to several human genes including GATA1 (GATA binding protein 1); GATA2 (GATA binding protein 2); and GATA3 (GATA binding protein 3). [provided by Alliance of Genome Resources, Apr 2022] |
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