Biguanides


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142 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 insulin INS_HUMAN INS Homo sapiens 3630 7950 102
2 protein kinase AMP-activated catalytic subunit alpha 2 AAPK2_HUMAN PRKAA2 Homo sapiens 5563 919 13
3 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 13
4 protein kinase AMP-activated catalytic subunit alpha 1 AAPK1_HUMAN PRKAA1 Homo sapiens 5562 812 12
5 solute carrier family 22 member 1 S22A1_HUMAN SLC22A1 Homo sapiens 6580 415 5
6 CREB regulated transcription coactivator 1 CRTC1_MOUSE Crtc1 Mus musculus 382056 993 4
7 dipeptidyl peptidase 4 DPP4_HUMAN DPP4 Homo sapiens 1803 1201 4
8 protein kinase AMP-activated non-catalytic subunit beta 1 AAKB1_HUMAN PRKAB1 Homo sapiens 5564 368 3
9 solute carrier family 22 member 2 S22A2_HUMAN SLC22A2 Homo sapiens 6582 255 3
10 cytochrome P450 family 4 subfamily F member 3 CP4F3_HUMAN CYP4F3 Homo sapiens 4051 2473 3
11 insulin receptor INSR_HUMAN INSR Homo sapiens 3643 748 3
12 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 3
13 glucagon GLUC_HUMAN GCG Homo sapiens 2641 671 2
14 chloride intracellular channel 1 CLIC1_HUMAN CLIC1 Homo sapiens 1192 76 2
15 serine/threonine kinase 11 STK11_HUMAN STK11 Homo sapiens 6794 365 2
16 C-X-C motif chemokine receptor 4 CXCR4_HUMAN CXCR4 Homo sapiens 7852 1170 2
17 PPARG coactivator 1 alpha PRGC1_PIG PPARGC1A Sus scrofa 397013 138 2
18 solute carrier family 22 (organic cation transporter), member 1 S22A1_MOUSE Slc22a1 Mus musculus 20517 116 2
19 lysine demethylase 1A KDM1A_HUMAN KDM1A Homo sapiens 23028 403 2
20 immunoglobulin heavy diversity 1-14 (non-functional) - IGHD1-14 Homo sapiens 28508 209 2
21 erb-b2 receptor tyrosine kinase 2 ERBB2_MOUSE Erbb2 Mus musculus 13866 567 2
22 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 2
23 SAFB like transcription modulator SLTM_HUMAN SLTM Homo sapiens 79811 394 2
24 prolactin induced protein PIP_RAT Pip Rattus norvegicus 64673 87 2
25 TSC complex subunit 1 TSC1_HUMAN TSC1 Homo sapiens 7248 220 2
26 cytochrome P450 family 2 subfamily C member 19 CP2CJ_HUMAN CYP2C19 Homo sapiens 1557 1098 2
27 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 2
28 solute carrier family 22 member 1 S22A1_RAT Slc22a1 Rattus norvegicus 24904 150 2
29 solute carrier family 29 member 4 S29A4_HUMAN SLC29A4 Homo sapiens 222962 113 2
30 heat shock protein family A (Hsp70) member 5 BIP_HUMAN HSPA5 Homo sapiens 3309 965 2
31 hemoglobin subunit alpha 1 HBA_HUMAN HBA1 Homo sapiens 3039 451 2
32 sucrase-isomaltase SUIS_HUMAN SI Homo sapiens 6476 1246 2
33 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 2
34 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 2
35 POU class 2 homeobox 2 PO2F2_HUMAN POU2F2 Homo sapiens 5452 995 2
36 serpin family E member 1 PAI1_HUMAN SERPINE1 Homo sapiens 5054 1182 2
37 eukaryotic translation initiation factor 4E binding protein 1 4EBP1_HUMAN EIF4EBP1 Homo sapiens 1978 300 2
38 LOC100508689 - LOC100508689 Homo sapiens 100508689 1114 1
39 poly (ADP-ribose) polymerase family, member 1 Q921K2_MOUSE Parp1 Mus musculus 11545 842 1
40 amyloid beta precursor protein A4_HUMAN APP Homo sapiens 351 3390 1
41 transforming growth factor alpha TGFA_HUMAN TGFA Homo sapiens 7039 974 1
42 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 1
43 cathepsin B CATB_HUMAN CTSB Homo sapiens 1508 1121 1
44 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 1
45 AT-rich interaction domain 4B ARI4B_HUMAN ARID4B Homo sapiens 51742 159 1
46 insulin like growth factor 1 receptor IGF1R_HUMAN IGF1R Homo sapiens 3480 814 1
47 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 1
48 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 1
49 coagulation factor II, thrombin THRB_HUMAN F2 Homo sapiens 2147 4706 1
50 immunoglobulin heavy constant epsilon - IGHE Homo sapiens 3497 1005 1