Protein Name glucagon
Organism Homo sapiens
Gene ID 2641
Gene Symbol


UniProt P01275 (GLUC_HUMAN)
Relationships Total Number of functionally related compound(s) : 671
Total Number of Articles : 2422


Gene Summary

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]

  • pro-glucagon
  • glicentin-related polypeptide
  • glucagon-like peptide 1
Click to show/hide the synonyms