Protein Name | sucrase-isomaltase |
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Organism | Homo sapiens |
Gene ID | 6476 |
Gene Symbol | SI |
UniProt | P14410 (SUIS_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
1246
Total Number of Articles : 1443 |
Description |
sucrase-isomaltase |
Gene Summary |
This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.[provided by RefSeq, Apr 2010] |
synonyms |
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Properties | |