Protein Name sucrase-isomaltase
Organism Homo sapiens
Gene ID 6476
Gene Symbol


UniProt P14410 (SUIS_HUMAN)
Relationships Total Number of functionally related compound(s) : 1246
Total Number of Articles : 1443


Gene Summary

This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.[provided by RefSeq, Apr 2010]

  • sucrase-isomaltase, intestinal
  • Alpha-methylglucosidase
  • Oligo-1,6-glucosidase
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