6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)-3,4-dihydroquinolin-2(1H)-one


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50 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 protein tyrosine kinase 2 FAK1_HUMAN PTK2 Homo sapiens 5747 1151 35
2 PTK2 protein tyrosine kinase 2 FAK1_MOUSE Ptk2 Mus musculus 14083 342 10
3 protein tyrosine kinase 2 FAK1_RAT Ptk2 Rattus norvegicus 25614 196 5
4 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 2
5 heat shock protein 5 BIP_MOUSE Hspa5 Mus musculus 14828 360 2
6 glial cell derived neurotrophic factor GDNF_HUMAN GDNF Homo sapiens 2668 388 1
7 integrin subunit beta 1 ITB1_HUMAN ITGB1 Homo sapiens 3688 582 1
8 ret proto-oncogene RET_HUMAN RET Homo sapiens 5979 674 1
9 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 1
10 Rac family small GTPase 1 RAC1_HUMAN RAC1 Homo sapiens 5879 884 1
11 tumor protein, translationally-controlled 1 TCTP_HUMAN TPT1 Homo sapiens 7178 191 1
12 prostaglandin D2 receptor PD2R_HUMAN PTGDR Homo sapiens 5729 491 1
13 prostaglandin-endoperoxide synthase 2 PGH2_MOUSE Ptgs2 Mus musculus 19225 1538 1
14 C-C motif chemokine ligand 2 CCL2_HUMAN CCL2 Homo sapiens 6347 1858 1
15 stanniocalcin 1 STC1_HUMAN STC1 Homo sapiens 6781 177 1
16 protein tyrosine kinase 2 beta FAK2_HUMAN PTK2B Homo sapiens 2185 848 1
17 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 1
18 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 1
19 tumor necrosis factor (ligand) superfamily, member 13b TN13B_MOUSE Tnfsf13b Mus musculus 24099 94 1
20 chemokine (C-C motif) ligand 2 CCL2_MOUSE Ccl2 Mus musculus 20296 1060 1
21 two pore segment channel 1 TPC1_HUMAN TPCN1 Homo sapiens 53373 129 1
22 matrix metallopeptidase 2 MMP2_RAT Mmp2 Rattus norvegicus 81686 772 1
23 C-X-C motif chemokine ligand 12 SDF1_HUMAN CXCL12 Homo sapiens 6387 628 1
24 leukotriene A4 hydrolase LKHA4_MOUSE Lta4h Mus musculus 16993 53 1
25 vascular endothelial growth factor A VEGFA_RAT Vegfa Rattus norvegicus 83785 1424 1
26 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 1
27 DNA-damage inducible transcript 3 DDIT3_MOUSE Ddit3 Mus musculus 13198 383 1
28 AKT serine/threonine kinase 1 AKT1_RAT Akt1 Rattus norvegicus 24185 2385 1
29 mitogen-activated protein kinase 3 MK03_MOUSE Mapk3 Mus musculus 26417 1527 1
30 angiopoietin 1 ANGP1_MOUSE Angpt1 Mus musculus 11600 128 1
31 nitric oxide synthase 2 NOS2_RAT Nos2 Rattus norvegicus 24599 1861 1
32 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 1
33 RAB5A, member RAS oncogene family RAB5A_HUMAN RAB5A Homo sapiens 5868 183 1
34 cellular communication network factor 2 CCN2_MOUSE Ccn2 Mus musculus 14219 258 1
35 endoplasmic reticulum (ER) to nucleus signalling 1 ERN1_MOUSE Ern1 Mus musculus 78943 162 1
36 aquaporin 1 (Colton blood group) AQP1_HUMAN AQP1 Homo sapiens 358 256 1
37 matrix metallopeptidase 14 MMP14_HUMAN MMP14 Homo sapiens 4323 391 1
38 bone morphogenetic protein 2 BMP2_MOUSE Bmp2 Mus musculus 12156 477 1
39 patched 1 PTC1_HUMAN PTCH1 Homo sapiens 5727 179 1
40 vascular endothelial growth factor C VEGFC_HUMAN VEGFC Homo sapiens 7424 221 1
41 RAP2B, member of RAS oncogene family RAP2B_HUMAN RAP2B Homo sapiens 5912 32 1
42 cellular communication network factor 1 CCN1_MOUSE Ccn1 Mus musculus 16007 62 1
43 focal adhesion kinase - PTK2 Sus scrofa 100170770 9 1
44 reversion-inducing-cysteine-rich protein with kazal motifs RECK_MOUSE Reck Mus musculus 53614 25 1
45 fibronectin 1 FINC_HUMAN FN1 Homo sapiens 2335 2017 1
46 left-right determination factor 2 LFTY2_HUMAN LEFTY2 Homo sapiens 7044 17 1
47 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 1
48 DNA damage inducible transcript 3 DDIT3_HUMAN DDIT3 Homo sapiens 1649 1082 1
49 SRC proto-oncogene, non-receptor tyrosine kinase SRC_HUMAN SRC Homo sapiens 6714 2142 1
50 TNF receptor superfamily member 10b TR10B_HUMAN TNFRSF10B Homo sapiens 8795 608 1