| Protein Name | protein tyrosine kinase 2 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 25614 |
| Gene Symbol | Ptk2 |
| UniProt | O35346 (FAK1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
196
Total Number of Articles : 288 |
Description |
protein tyrosine kinase 2 |
| Gene Summary |
Enables several functions, including identical protein binding activity; integrin binding activity; and phosphatidylinositol 3-kinase binding activity. Involved in several processes, including cellular response to morphine; positive regulation of cell population proliferation; and regulation of cell migration. Located in several cellular components, including basolateral plasma membrane; focal adhesion; and intercalated disc. Is active in glutamatergic synapse and postsynapse. Used to study hepatocellular carcinoma; hypertension; and nephritis. Biomarker of hypertension; ischemia; and uremia. Human ortholog(s) of this gene implicated in leiomyoma; lung small cell carcinoma; and pulmonary hypertension. Orthologous to human PTK2 (protein tyrosine kinase 2). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |