Protein Name | matrix metallopeptidase 2 |
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Organism | Rattus norvegicus |
Gene ID | 81686 |
Gene Symbol | Mmp2 |
UniProt | P33436 (MMP2_RAT) |
Relationships |
Total Number of functionally related compound(s) :
772
Total Number of Articles : 1132 |
Description |
matrix metallopeptidase 2 |
Gene Summary |
Enables fibronectin binding activity and peptidase activity. Involved in several processes, including cellular response to estradiol stimulus; circulatory system development; and reproductive structure development. Located in extracellular space. Used to study artery disease (multiple); conjunctivitis; proteinuria; and transient cerebral ischemia. Biomarker of several diseases, including acute necrotizing pancreatitis; artery disease (multiple); bile duct disease (multiple); brain ischemia (multiple); and liver cirrhosis (multiple). Human ortholog(s) of this gene implicated in artery disease (multiple); eye disease (multiple); pseudoxanthoma elasticum; and temporal arteritis. Orthologous to human MMP2 (matrix metallopeptidase 2). [provided by Alliance of Genome Resources, Jul 2025] |
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