Protein Name matrix metallopeptidase 2
Organism Rattus norvegicus
Gene ID 81686
Gene Symbol

Mmp2

UniProt P33436 (MMP2_RAT)
Relationships Total Number of functionally related compound(s) : 772
Total Number of Articles : 1132
Description

matrix metallopeptidase 2

Gene Summary

Enables fibronectin binding activity and peptidase activity. Involved in several processes, including cellular response to estradiol stimulus; circulatory system development; and reproductive structure development. Located in extracellular space. Used to study artery disease (multiple); conjunctivitis; proteinuria; and transient cerebral ischemia. Biomarker of several diseases, including acute necrotizing pancreatitis; artery disease (multiple); bile duct disease (multiple); brain ischemia (multiple); and liver cirrhosis (multiple). Human ortholog(s) of this gene implicated in artery disease (multiple); eye disease (multiple); pseudoxanthoma elasticum; and temporal arteritis. Orthologous to human MMP2 (matrix metallopeptidase 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • 72 kDa type IV collagenase
  • 72 kDa gelatinase
  • MMP-2
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Properties