Protein Name PTK2 protein tyrosine kinase 2
Organism Mus musculus
Gene ID 14083
Gene Symbol


UniProt P34152 (FAK1_MOUSE)
Relationships Total Number of functionally related compound(s) : 342
Total Number of Articles : 450

PTK2 protein tyrosine kinase 2

Gene Summary

Enables non-membrane spanning protein tyrosine kinase activity. Involved in positive regulation of cell population proliferation; positive regulation of ubiquitin-dependent protein catabolic process; and protein phosphorylation. Acts upstream of or within several processes, including blood vessel morphogenesis; generation of neurons; and peptidyl-tyrosine autophosphorylation. Located in several cellular components, including apical plasma membrane; focal adhesion; and lamellipodium. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and yolk sac. Human ortholog(s) of this gene implicated in leiomyoma; lung small cell carcinoma; and pulmonary hypertension. Orthologous to human PTK2 (protein tyrosine kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

  • focal adhesion kinase 1
  • focal adhesion kinase-related nonkinase
  • focal ashension kinase 1
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