adavosertib


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122 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 WEE1 G2 checkpoint kinase WEE1_HUMAN WEE1 Homo sapiens 7465 177 166
2 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 25
3 cyclin dependent kinase 1 CDK1_HUMAN CDK1 Homo sapiens 983 1023 23
4 WEE 1 homolog 1 (S. pombe) WEE1_MOUSE Wee1 Mus musculus 22390 28 14
5 checkpoint kinase 1 CHK1_HUMAN CHEK1 Homo sapiens 1111 648 12
6 polo like kinase 1 PLK1_HUMAN PLK1 Homo sapiens 5347 475 7
7 H2A.X variant histone H2AX_HUMAN H2AX Homo sapiens 3014 412 5
8 cyclin dependent kinase 2 CDK2_HUMAN CDK2 Homo sapiens 1017 1201 5
9 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 4
10 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 3
11 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 3
12 cyclin dependent kinase 12 CDK12_HUMAN CDK12 Homo sapiens 51755 58 3
13 myelin transcription factor 1 MYT1_HUMAN MYT1 Homo sapiens 4661 42 3
14 RAD51 recombinase RAD51_HUMAN RAD51 Homo sapiens 5888 537 3
15 transformation related protein 53 P53_MOUSE Trp53 Mus musculus 22059 281 3
16 ATR serine/threonine kinase ATR_HUMAN ATR Homo sapiens 545 866 3
17 ataxia telangiectasia mutated ATM_MOUSE Atm Mus musculus 11920 222 2
18 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 2
19 H2A.X variant histone H2AX_MOUSE H2ax Mus musculus 15270 247 2
20 ATRX chromatin remodeler ATRX_HUMAN ATRX Homo sapiens 546 85 2
21 MUS81 structure-specific endonuclease subunit MUS81_HUMAN MUS81 Homo sapiens 80198 37 2
22 DNA damage inducible transcript 3 DDIT3_HUMAN DDIT3 Homo sapiens 1649 1082 2
23 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 2
24 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 2
25 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 2
26 Kirsten rat sarcoma viral oncogene homolog RASK_MOUSE Kras Mus musculus 16653 464 2
27 cyclin-dependent kinase 1 CDK1_MOUSE Cdk1 Mus musculus 12534 208 2
28 CD8a molecule CD8A_HUMAN CD8A Homo sapiens 925 1925 1
29 MIR7-3 host gene - MIR7-3HG Homo sapiens 284424 679 1
30 Yes1 associated transcriptional regulator YAP1_HUMAN YAP1 Homo sapiens 10413 666 1
31 myeloblastosis oncogene-like 2 MYBB_MOUSE Mybl2 Mus musculus 17865 13 1
32 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 1
33 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 1
34 S-phase kinase associated protein 2 SKP2_HUMAN SKP2 Homo sapiens 6502 235 1
35 RELA proto-oncogene, NF-kB subunit TF65_HUMAN RELA Homo sapiens 5970 1514 1
36 syndecan 1 SDC1_HUMAN SDC1 Homo sapiens 6382 265 1
37 H2B clustered histone 21 H2B2E_HUMAN H2BC21 Homo sapiens 8349 181 1
38 E2F transcription factor 1 E2F1_HUMAN E2F1 Homo sapiens 1869 403 1
39 poly (ADP-ribose) polymerase family, member 1 Q921K2_MOUSE Parp1 Mus musculus 11545 842 1
40 myelocytomatosis oncogene MYC_MOUSE Myc Mus musculus 17869 289 1
41 ATP-binding cassette, sub-family B (MDR/TAP), member 1B MDR1B_MOUSE Abcb1b Mus musculus 18669 469 1
42 checkpoint kinase 2 CHK2_HUMAN CHEK2 Homo sapiens 11200 417 1
43 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 1
44 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 1
45 BH3 interacting domain death agonist BID_HUMAN BID Homo sapiens 637 1130 1
46 annexin A5 ANXA5_HUMAN ANXA5 Homo sapiens 308 1785 1
47 H3 histone pseudogene 16 - H3P16 Homo sapiens 644914 2095 1
48 SRC proto-oncogene, non-receptor tyrosine kinase SRC_HUMAN SRC Homo sapiens 6714 2142 1
49 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 1
50 nuclear receptor coactivator 4 NCOA4_HUMAN NCOA4 Homo sapiens 8031 81 1