Protein Name cyclin dependent kinase 1
Organism Mus musculus
Gene ID 12534
Gene Symbol

Cdk1

UniProt P11440 (CDK1_MOUSE)
Relationships Total Number of functionally related compound(s) : 208
Total Number of Articles : 261
Description

cyclin dependent kinase 1

Gene Summary

Enables Hsp70 protein binding activity; chromatin binding activity; and cyclin-dependent protein serine/threonine kinase activity. Acts upstream of or within several processes, including mitotic G2 DNA damage checkpoint signaling; mitotic cell cycle phase transition; and protein phosphorylation. Colocalizes with mitochondrial matrix. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in breast cancer; cervical cancer; and urinary bladder cancer. Orthologous to human CDK1 (cyclin dependent kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • cyclin-dependent kinase 1
  • cell cycle p34 CDC2 kinase protein
  • cell division control protein 2 homolog
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Properties