| Protein Name | H2A.X variant histone |
|---|---|
| Organism | Mus musculus |
| Gene ID | 15270 |
| Gene Symbol | H2ax |
| UniProt | P27661 (H2AX_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
247
Total Number of Articles : 296 |
Description |
H2A.X variant histone |
| Gene Summary |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. [provided by RefSeq, Nov 2015] |
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| Properties | |