adavosertib

checkpoint kinase 1 ; Homo sapiens







12 Article(s)
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Title
Pub. Year
#Total Relationships
1 31209198 Targeting the cell cycle in head and neck cancer by Chk1 inhibition: a novel concept of bimodal cell death. 2019 Jun 17 1
2 31717700 Synergism Through WEE1 and CHK1 Inhibition in Acute Lymphoblastic Leukemia. 2019 Oct 25 1
3 27939202 G2-checkpoint targeting and radiosensitization of HPV/p16-positive HNSCC cells through the inhibition of Chk1 and Wee1. 2017 Feb 1
4 28698200 Targeting AXL and mTOR Pathway Overcomes Primary and Acquired Resistance to WEE1 Inhibition in Small-Cell Lung Cancer. 2017 Oct 15 1
5 25283841 A regimen combining the Wee1 inhibitor AZD1775 with HDAC inhibitors targets human acute myeloid leukemia cells harboring various genetic mutations. 2015 Apr 2
6 25308916 Targeting histone deacetylases (HDACs) and Wee1 for treating high-risk neuroblastoma. 2015 Jan 1
7 25458954 Synergistic antitumor interactions between MK-1775 and panobinostat in preclinical models of pancreatic cancer. 2015 Jan 28 2
8 26529495 Synergistic anti-leukemic interactions between panobinostat and MK-1775 in acute myeloid leukemia ex vivo. 2015 4
9 24179152 CHK1 and WEE1 inhibition combine synergistically to enhance therapeutic efficacy in acute myeloid leukemia ex vivo. 2014 Apr 1
10 25084614 CHK1 plays a critical role in the anti-leukemic activity of the wee1 inhibitor MK-1775 in acute myeloid leukemia cells. 2014 Aug 1 3
11 25301733 Pharmacological targeting the ATR-CHK1-WEE1 axis involves balancing cell growth stimulation and apoptosis. 2014 Nov 15 1
12 23148684 Unique functions of CHK1 and WEE1 underlie synergistic anti-tumor activity upon pharmacologic inhibition. 2012 Nov 13 1