Protein Name WEE1 G2 checkpoint kinase
Organism Homo sapiens
Gene ID 7465
Gene Symbol

WEE1

UniProt P30291 (WEE1_HUMAN), Q86V29 (Q86V29_HUMAN)
Relationships Total Number of functionally related compound(s) : 177
Total Number of Articles : 339
Description

WEE1 G2 checkpoint kinase

Gene Summary

This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008]

synonyms
  • wee1-like protein kinase
  • WEE1 homolog
  • WEE1+ homolog
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Properties