Protein Name | WEE1 G2 checkpoint kinase |
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Organism | Homo sapiens |
Gene ID | 7465 |
Gene Symbol | WEE1 |
UniProt | P30291 (WEE1_HUMAN), Q86V29 (Q86V29_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
177
Total Number of Articles : 339 |
Description |
WEE1 G2 checkpoint kinase |
Gene Summary |
This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008] |
synonyms |
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Properties | |