| Protein Name | polo like kinase 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 5347 |
| Gene Symbol | PLK1 |
| UniProt | P53350 (PLK1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
475
Total Number of Articles : 766 |
Description |
polo like kinase 1 |
| Gene Summary |
The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015] |
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