Protein Name protein kinase, DNA-activated, catalytic subunit
Organism Homo sapiens
Gene ID 5591
Gene Symbol

PRKDC

UniProt P78527 (PRKDC_HUMAN)
Relationships Total Number of functionally related compound(s) : 418
Total Number of Articles : 716
Description

protein kinase, DNA-activated, catalytic subunit

Gene Summary

This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]

synonyms
  • DNA-dependent protein kinase catalytic subunit
  • DNA-PK catalytic subunit
  • hyper-radiosensitivity of murine scid mutation, complementing 1
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Properties