pazopanib


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230 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 80
2 kinase insert domain receptor VGFR2_HUMAN KDR Homo sapiens 3791 1635 68
3 KIT proto-oncogene, receptor tyrosine kinase KIT_HUMAN KIT Homo sapiens 3815 679 36
4 fms related receptor tyrosine kinase 1 VGFR1_HUMAN FLT1 Homo sapiens 2321 547 29
5 platelet derived growth factor receptor beta PGFRB_HUMAN PDGFRB Homo sapiens 5159 417 28
6 platelet derived growth factor receptor alpha PGFRA_HUMAN PDGFRA Homo sapiens 5156 229 22
7 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 11
8 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 8
9 B-Raf proto-oncogene, serine/threonine kinase BRAF_HUMAN BRAF Homo sapiens 673 872 7
10 fibroblast growth factor receptor 2 FGFR2_HUMAN FGFR2 Homo sapiens 2263 228 6
11 UDP glucuronosyltransferase family 1 member A1 UD11_HUMAN UGT1A1 Homo sapiens 54658 747 6
12 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 6
13 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 6
14 vascular endothelial growth factor A VEGFA_MOUSE Vegfa Mus musculus 22339 1647 6
15 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 6
16 MET proto-oncogene, receptor tyrosine kinase MET_HUMAN MET Homo sapiens 4233 791 5
17 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 5
18 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 4
19 fms related receptor tyrosine kinase 4 VGFR3_HUMAN FLT4 Homo sapiens 2324 142 4
20 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 4
21 ASPSCR1 tether for SLC2A4, UBX domain containing ASPC1_HUMAN ASPSCR1 Homo sapiens 79058 33 4
22 vascular endothelial growth factor A VEGFA_RAT Vegfa Rattus norvegicus 83785 1424 4
23 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 3
24 solute carrier organic anion transporter family member 1B1 SO1B1_HUMAN SLCO1B1 Homo sapiens 10599 575 3
25 heat shock protein 90 alpha family class A member 1 HS90A_HUMAN HSP90AA1 Homo sapiens 3320 1552 3
26 beclin 1 BECN1_HUMAN BECN1 Homo sapiens 8678 847 3
27 Yes1 associated transcriptional regulator YAP1_HUMAN YAP1 Homo sapiens 10413 666 3
28 eukaryotic translation initiation factor 2A EIF2A_HUMAN EIF2A Homo sapiens 83939 566 3
29 hepatocyte growth factor HGF_HUMAN HGF Homo sapiens 3082 1036 3
30 TXK tyrosine kinase TXK_HUMAN TXK Homo sapiens 7294 195 3
31 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 2
32 T-box transcription factor 1 TBX1_HUMAN TBX1 Homo sapiens 6899 869 2
33 carbonic anhydrase 9 CAH9_HUMAN CA9 Homo sapiens 768 645 2
34 placental growth factor PLGF_HUMAN PGF Homo sapiens 5228 355 2
35 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 2
36 phosphoglycolate phosphatase PGP_HUMAN PGP Homo sapiens 283871 1342 2
37 heat shock protein family A (Hsp70) member 5 BIP_HUMAN HSPA5 Homo sapiens 3309 965 2
38 KIT ligand SCF_HUMAN KITLG Homo sapiens 4254 644 2
39 NRAS proto-oncogene, GTPase RASN_HUMAN NRAS Homo sapiens 4893 357 2
40 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 2
41 TIMP metallopeptidase inhibitor 1 TIMP1_HUMAN TIMP1 Homo sapiens 7076 734 2
42 secreted phosphoprotein 1 OSTP_HUMAN SPP1 Homo sapiens 6696 1527 2
43 fibroblast growth factor receptor 1 FGFR1_HUMAN FGFR1 Homo sapiens 2260 405 2
44 platelet derived growth factor receptor, beta polypeptide PGFRB_MOUSE Pdgfrb Mus musculus 18596 179 2
45 solute carrier family 17 member 5 S17A5_HUMAN SLC17A5 Homo sapiens 26503 791 2
46 heparan sulfate proteoglycan 2 PGBM_HUMAN HSPG2 Homo sapiens 3339 545 2
47 glutamic--pyruvic transaminase ALAT1_HUMAN GPT Homo sapiens 2875 774 2
48 interferon alpha 1 IFNA1_HUMAN IFNA1 Homo sapiens 3439 1490 2
49 zinc fingers and homeoboxes 2 ZHX2_HUMAN ZHX2 Homo sapiens 22882 627 2
50 phosphoglycolate phosphatase PGP_MOUSE Pgp Mus musculus 67078 756 2