pazopanib

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







11 Article(s)
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1 33723657 Is there association between clinically relevant toxicities of pazopanib and sunitinib with the use of weak CYP3A4 and P-gp inhibitors? 2021 Sep 1
2 31535851 Involvement of Pazopanib and Sunitinib Aldehyde Reactive Metabolites in Toxicity and Drug-Drug Interactions in Vitro and in Patient Samples. 2020 Jan 21 2
3 31932871 Association between clinically relevant toxicities of pazopanib and sunitinib and the use of weak CYP3A4 and P-gp inhibitors. 2020 Apr 1
4 30367352 Impact of CYP3A4*22 on Pazopanib Pharmacokinetics in Cancer Patients. 2019 May 3
5 29440451 Establishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human Hepatocytes. 2018 May 1
6 29464464 Pazopanib-related tumor lysis syndrome in metastatic clear cell renal cell carcinoma: a case report. 2018 Jun 1
7 25737032 Metabolic behavior prediction of pazopanib by cytochrome P450 (CYP) 3A4 by molecular docking. 2016 Aug 7
8 24800949 Phase I study of weekly paclitaxel in combination with pazopanib and lapatinib in advanced solid malignancies. 2014 May 27 1
9 23636448 Effects of ketoconazole and esomeprazole on the pharmacokinetics of pazopanib in patients with solid tumors. 2013 Jun 3
10 25819130 [Management of side effects of targeted therapies in renal cancer: iatrogenic side effects]. 2011 1
11 20881954 An evaluation of the drug interaction potential of pazopanib, an oral vascular endothelial growth factor receptor tyrosine kinase inhibitor, using a modified Cooperstown 5+1 cocktail in patients with advanced solid tumors. 2010 Nov 1