rucaparib


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111 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 136
2 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 61
3 BRCA2 DNA repair associated BRCA2_HUMAN BRCA2 Homo sapiens 675 305 19
4 collagen type XI alpha 2 chain COBA2_HUMAN COL11A2 Homo sapiens 1302 794 11
5 poly(ADP-ribose) polymerase 2 PARP2_HUMAN PARP2 Homo sapiens 10038 107 7
6 poly (ADP-ribose) polymerase family, member 1 Q921K2_MOUSE Parp1 Mus musculus 11545 842 7
7 RAD51 recombinase RAD51_HUMAN RAD51 Homo sapiens 5888 537 7
8 poly(ADP-ribose) polymerase family member 3 PARP3_HUMAN PARP3 Homo sapiens 10039 44 5
9 RAD51 paralog C RA51C_HUMAN RAD51C Homo sapiens 5889 22 4
10 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 4
11 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 4
12 partner and localizer of BRCA2 PALB2_HUMAN PALB2 Homo sapiens 79728 35 3
13 phosphoglycolate phosphatase PGP_HUMAN PGP Homo sapiens 283871 1342 2
14 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 2
15 hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase G6PE_HUMAN H6PD Homo sapiens 9563 280 2
16 ADP-ribosyltransferase 1 NAR1_HUMAN ART1 Homo sapiens 417 42 2
17 RAD51 paralog D RA51D_HUMAN RAD51D Homo sapiens 5892 37 2
18 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 2
19 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 2
20 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 2
21 ETS transcription factor ERG ERG_HUMAN ERG Homo sapiens 2078 1044 2
22 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 2
23 myosin light chain kinase MYLK_HUMAN MYLK Homo sapiens 4638 298 2
24 protein tyrosine kinase 2 beta FAK2_HUMAN PTK2B Homo sapiens 2185 848 2
25 cytochrome P450 family 2 subfamily C member 19 CP2CJ_HUMAN CYP2C19 Homo sapiens 1557 1098 2
26 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 2
27 annexin A5 ANXA5_HUMAN ANXA5 Homo sapiens 308 1785 2
28 poly(ADP-ribose) polymerase family member 4 PARP4_HUMAN PARP4 Homo sapiens 143 12 2
29 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 1
30 ERCC excision repair 1, endonuclease non-catalytic subunit ERCC1_HUMAN ERCC1 Homo sapiens 2067 239 1
31 cytochrome P450 family 2 subfamily C member 9 CP2C9_HUMAN CYP2C9 Homo sapiens 1559 1244 1
32 Pim-1 proto-oncogene, serine/threonine kinase PIM1_HUMAN PIM1 Homo sapiens 5292 562 1
33 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 1
34 thymocyte selection associated high mobility group box TOX_HUMAN TOX Homo sapiens 9760 202 1
35 tankyrase TNKS1_HUMAN TNKS Homo sapiens 8658 163 1
36 twist family bHLH transcription factor 1 TWST1_HUMAN TWIST1 Homo sapiens 7291 370 1
37 deoxycytidine kinase DCK_HUMAN DCK Homo sapiens 1633 234 1
38 ALK receptor tyrosine kinase ALK_HUMAN ALK Homo sapiens 238 603 1
39 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 1
40 cytochrome P450 family 1 subfamily A member 2 CP1A2_HUMAN CYP1A2 Homo sapiens 1544 1532 1
41 ATP binding cassette subfamily B member 6 (Langereis blood group) ABCB6_HUMAN ABCB6 Homo sapiens 10058 793 1
42 cytochrome P450 family 2 subfamily D member 6 CP2D6_HUMAN CYP2D6 Homo sapiens 1565 1531 1
43 ATP-binding cassette, sub-family B (MDR/TAP), member 1B MDR1B_MOUSE Abcb1b Mus musculus 18669 469 1
44 cyclin dependent kinase 1 CDK1_HUMAN CDK1 Homo sapiens 983 1023 1
45 glutamic--pyruvic transaminase ALAT1_HUMAN GPT Homo sapiens 2875 774 1
46 ATP-binding cassette, sub-family B (MDR/TAP), member 1A MDR1A_MOUSE Abcb1a Mus musculus 18671 272 1
47 interferon alpha 1 IFNA1_HUMAN IFNA1 Homo sapiens 3439 1490 1
48 galactosidase beta 1 BGAL_HUMAN GLB1 Homo sapiens 2720 1142 1
49 cytochrome P450 family 2 subfamily B member 6 CP2B6_HUMAN CYP2B6 Homo sapiens 1555 1488 1
50 estrogen receptor 1 ESR1_HUMAN ESR1 Homo sapiens 2099 3003 1