rucaparib

BRCA1 DNA repair associated ; Homo sapiens







61 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34958553 Proteomic Analysis Reveals Low-Dose PARP Inhibitor-Induced Differential Protein Expression in BRCA1-Mutated High-Grade Serous Ovarian Cancer Cells. 2022 Feb 2 1
2 35205643 Precision Medicine for BRCA/PALB2-Mutated Pancreatic Cancer and Emerging Strategies to Improve Therapeutic Responses to PARP Inhibition. 2022 Feb 11 1
3 35210863 Guidelines for Management of Treatment-Emergent Adverse Events During Rucaparib Treatment of Patients with Metastatic Castration-Resistant Prostate Cancer. 2022 1
4 35298905 Rucaparib for BRCA1/2-mutated pretreated ovarian cancer: reflections from the ARIEL4 trial. 2022 Apr 1
5 35594523 The growing role of rucaparib in contemporary treatment of metastatic prostate cancer: a review of efficacy and guidance for side effect management. 2022 May 26 1
6 35614267 Imaging PARP with [18F]rucaparib in pancreatic cancer models. 2022 May 26 1
7 33145877 FDA Approval Summary: Rucaparib for the Treatment of Patients with Deleterious BRCA-Mutated Metastatic Castrate-Resistant Prostate Cancer. 2021 Feb 2
8 33515503 Rucaparib in patients with BAP1-deficient or BRCA1-deficient mesothelioma (MiST1): an open-label, single-arm, phase 2a clinical trial. 2021 Jun 1
9 33753748 Cisplatin +/- rucaparib after preoperative chemotherapy in patients with triple-negative or BRCA mutated breast cancer. 2021 Mar 22 1
10 33827356 Olaparib and rucaparib for the treatment of DNA repair-deficient metastatic castration-resistant prostate cancer. 2021 Aug 1
11 33941784 Molecular and clinical determinants of response and resistance to rucaparib for recurrent ovarian cancer treatment in ARIEL2 (Parts 1 and 2). 2021 May 3 1
12 33970687 Phase II Study of Maintenance Rucaparib in Patients With Platinum-Sensitive Advanced Pancreatic Cancer and a Pathogenic Germline or Somatic Variant in BRCA1, BRCA2, or PALB2. 2021 Aug 1 2
13 34103386 Rucaparib maintenance treatment for recurrent ovarian carcinoma: the effects of progression-free interval and prior therapies on efficacy and safety in the randomized phase III trial ARIEL3. 2021 Jul 1
14 34459606 Copper-Mediated Radiosynthesis of [18F]Rucaparib. 2021 Sep 17 1
15 34549539 Maintenance treatment with rucaparib for recurrent ovarian carcinoma in ARIEL3, a randomized phase 3 trial: The effects of best response to last platinum-based regimen and disease at baseline on efficacy and safety. 2021 Oct 1
16 34598946 Response to Rucaparib in BRCA-Mutant Metastatic Castration-Resistant Prostate Cancer Identified by Genomic Testing in the TRITON2 Study. 2021 Dec 15 1
17 34778690 Differential Activity of PARP Inhibitors in BRCA1- Versus BRCA2-Altered Metastatic Castration-Resistant Prostate Cancer. 2021 1
18 34904808 PARP Inhibition in Advanced Prostate Cancer. 2021 Nov-Dec 01 1
19 32367009 PARP inhibitors as a new therapeutic option in metastatic prostate cancer: a systematic review. 2020 Dec 1
20 32371137 'PARP'ing fibrosis: repurposing poly (ADP ribose) polymerase (PARP) inhibitors. 2020 Jul 1
21 32427631 Poly(ADP-ribose) polymerase inhibitors in prostate and urothelial cancer. 2020 Jul 1
22 32717529 The ups and downs of Poly(ADP-ribose) Polymerase-1 inhibitors in cancer therapy-Current progress and future direction. 2020 Oct 1 1
23 32795228 Rucaparib in Men With Metastatic Castration-Resistant Prostate Cancer Harboring a BRCA1 or BRCA2 Gene Alteration. 2020 Nov 10 1
24 32814685 When and How to Use PARP Inhibitors in Prostate Cancer: A Systematic Review of the Literature with an Update on On-Going Trials. 2020 Oct 1
25 32927276 BET, SRC, and BCL2 family inhibitors are synergistic drug combinations with PARP inhibitors in ovarian cancer. 2020 Oct 1
26 32963528 BRCA Mutations in Prostate Cancer: Prognostic and Predictive Implications. 2020 1
27 29166829 Rucaparib: A Poly(ADP-Ribose) Polymerase Inhibitor for BRCA-Mutated Relapsed Ovarian Cancer. 2019 Apr 2
28 30425037 BRCA Reversion Mutations in Circulating Tumor DNA Predict Primary and Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma. 2019 Feb 3
29 30589644 PARP inhibition enhances tumor cell-intrinsic immunity in ERCC1-deficient non-small cell lung cancer. 2019 Mar 1 1
30 30830551 Rucaparib: A Review in Ovarian Cancer. 2019 Apr 1
31 30912451 Advances in the use of PARP inhibitors for BRCA1/2-associated breast cancer: talazoparib. 2019 May 1
32 30939057 Germline BRCA1 Deletion as Driver Mutation for Metastatic Urachal Adenocarcinoma in Patient Who Achieved Complete Response to Rucaparib. 2019 May 1
33 30940721 Maintenance Rucaparib Controls Some Pancreatic Cancers. 2019 Jun 1
34 31069647 Current Systemic Treatment Landscape of Advanced Gynecologic Malignancies. 2019 Jun 1
35 31191001 Current status and future prospects of PARP inhibitor clinical trials in ovarian cancer. 2019 1
36 31404966 Clinical Development of PARP Inhibitors in Treating Metastatic Castration-Resistant Prostate Cancer. 2019 Aug 9 1
37 31685558 Antitumor activity of the poly(ADP-ribose) polymerase inhibitor rucaparib as monotherapy in patients with platinum-sensitive, relapsed, BRCA-mutated, high-grade ovarian cancer, and an update on safety. 2019 Nov 3
38 29189915 Targeting BRCA1/2 deficient ovarian cancer with CNDAC-based drug combinations. 2018 Feb 1
39 29605737 Rucaparib: An emerging parp inhibitor for treatment of recurrent ovarian cancer. 2018 May 1
40 29606854 Rucaparib: a novel PARP inhibitor for BRCA advanced ovarian cancer. 2018 1
41 29977351 Rucaparib in ovarian cancer: an update on safety, efficacy and place in therapy. 2018 1
42 30051098 Rucaparib Monotherapy in Patients With Pancreatic Cancer and a Known Deleterious BRCA Mutation. 2018 1
43 30105925 Rucaparib in ovarian cancer: extending the use of PARP inhibitors in the recurrent disease. 2018 Dec 2
44 30266954 Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma. 2018 Sep 28 4
45 30426062 Pharmacokinetics and clinical response to single agent rucaparib in a dialysis dependent patient with BRCA associated breast and recurrent ovarian cancer. 2018 Nov 2
46 30535808 Using PARP Inhibitors in the Treatment of Patients With Ovarian Cancer. 2018 Nov 15 1
47 28057616 Rucaparib Approved for Ovarian Cancer. 2017 Feb 1
48 28222073 A phase I study of intravenous and oral rucaparib in combination with chemotherapy in patients with advanced solid tumours. 2017 Mar 28 1
49 28250698 Pharmaceutical Approval Update. 2017 Mar 1
50 28264872 A Phase I-II Study of the Oral PARP Inhibitor Rucaparib in Patients with Germline BRCA1/2-Mutated Ovarian Carcinoma or Other Solid Tumors. 2017 Aug 1 2